Following their discovery over 50 years ago, mesenchymal stromal cells (MSCs) have
become one of the most studied cellular therapeutic products by both academia and industry …

Mesenchymal stem cell secretome or conditioned medium (MSC-CM) is a combination of
biomolecules and growth factors in cell culture growth medium, secreted by mesenchymal …

Mesenchymal stem cells (MSCs) have been used in clinic for approximately 20 years.
During this period, various new populations of MSCs have been found or manipulated …

Bone morphogenetic protein-2 (BMP-2) is a potent growth factor affecting bone formation.
While recombinant human BMP-2 (rhBMP-2) has been commercially available in cases of …

Osteoporosis is a skeletal disorder marked by compromised bone integrity, predisposing
individuals, particularly older adults and postmenopausal women, to fractures. The advent of …

The gel microsphere culture system (GMCS) showed various advantages for mesenchymal
stem cell (MSC) expansion and delivery, such as high specific surface area, small and …

Abstract Background Mesenchymal stem cells (MSCs) are undifferentiated cells that can
give rise to a mesoderm lineage. Adipose-derived MSCs are an easy and accessible source …

Background The dog represents an excellent large animal model for translational cell-based
studies. Importantly, the properties of canine multipotent stromal cells (cMSCs) and the ideal …

Continued improvements in the understanding and application of mesenchymal stem cells
(MSC) have revolutionized tissue engineering. This is particularly true within the field of …

Introduction: Cell-based therapies exploit the heterogeneous and self-sufficient biological
environment of stem cells to restore, maintain and improve tissue functions. Adipose-derived …