Interleukin-1 (IL-1) family of cytokines: role in type 2 diabetes

M Banerjee, M Saxena - Clinica chimica acta, 2012 - Elsevier
Cytokines are small cell signaling protein molecules which encompass a large and diverse
family. They consist of immunomodulating agents such as interleukins and inteferons …

Genetic polymorphisms of cytokine genes in type 2 diabetes mellitus

M Banerjee, M Saxena - World journal of diabetes, 2014 - pmc.ncbi.nlm.nih.gov
Diabetes mellitus is a combined metabolic disorder which includes hyperglycemia,
dyslipidemia, stroke and several other complications. Various groups all over the world are …

Association of glutathione S-transferase (GSTM1, T1 and P1) gene polymorphisms with type 2 diabetes mellitus in north Indian population

HK Bid, R Konwar, M Saxena… - Journal of …, 2010 - journals.lww.com
Background: Diabetes mellitus is associated with an increased production of reactive
oxygen species (ROS) and a reduction in antioxidant defense. The oxidative stress becomes …

Vitamin D receptor gene polymorphisms among Emirati patients with type 2 diabetes mellitus

H Al Safar, SEH Chehadeh, L Abdel-Wareth… - The Journal of steroid …, 2018 - Elsevier
At a prevalence rate close to 19.5%, the UAE has one of the highest rates of Type 2
Diabetes Mellitus (T2DM) in the world. Genome wide association studies (GWAS) have led …

Expression of immune‐inflammatory markers in sites of chronic periodontitis in patients with type 2 diabetes

PM Duarte, T Szeremeske Miranda… - Journal of …, 2012 - Wiley Online Library
Background: The aim of this study is to evaluate the gene expression of immune‐
inflammatory markers in gingival biopsies of patients with type 2 diabetes with chronic …

Interleukin‐4 genetic variants correlate with its transcript and protein levels in patients with vitiligo

M Imran, NC Laddha, M Dwivedi… - British Journal of …, 2012 - academic.oup.com
Background Vitiligo is an acquired pigmentary disorder resulting from loss of melanocytes.
Interleukin (IL)‐4 has been shown to stimulate B‐cell proliferation, to regulate …

The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population

G Kalkan, N Karakus, Y Baş, Z Takçı, P Özuğuz, Ö Ateş… - Gene, 2013 - Elsevier
Objective Alopecia areata (AA) is hypothesized to be an organ-specific autoimmune disease
of hair follicles mediated by T cells. As immunological and genetic factors have been …

Genetic etiology of type 2 diabetes mellitus: a review

UJ Kommoju, BM Reddy - International Journal of Diabetes in Develo** …, 2011 - Springer
Type 2 diabetes mellitus (T2DM) is the most common form of diabetes characterized by
elevated levels of plasma glucose caused by impairment in both insulin secretion and …

The association of insertions/deletions (INDELs) and variable number tandem repeats (VNTRs) with obesity and its related traits and complications

YH Say - Journal of physiological anthropology, 2017 - Springer
Background Despite the fact that insertions/deletions (INDELs) are the second most
common type of genetic variations and variable number tandem repeats (VNTRs) represent …

Systemic cytokines in type 2 diabetes mellitus and chronic periodontitis

AB Acharya, S Thakur, MV Muddapur… - Current diabetes …, 2018 - ingentaconnect.com
Background: Cytokine dysregulation plays an important role in Type 2 Diabetes Mellitus
(T2DM) and Chronic Periodontitis (CP) with a commonality in pathogenic mechanisms. CP …