Thermoplastic nanofluidic devices for biomedical applications

KM Weerakoon-Ratnayake, CE O'Neil, FI Uba… - Lab on a Chip, 2017 - pubs.rsc.org
Microfluidics is now moving into a developmental stage where basic discoveries are being
transitioned into the commercial sector so that these discoveries can affect, for example …

Nanofluidic devices for the separation of biomolecules

C Rathnayaka, CA Amarasekara, K Akabirov… - … of Chromatography A, 2022 - Elsevier
Over the last 30-years, microchip electrophoresis and its applications have expanded due to
the benefits it offers. Nanochip electrophoresis, on the other hand, is viewed as an evolving …

Incorporation of a Morphologically Controlled Ice Grain Boundary into a Microfluidic Device for Size-Selective Separation of Micro/Nanospheres

J Kimijima, A Inagawa, N Uehara - Analytical Chemistry, 2023 - ACS Publications
A frozen aqueous solution was integrated into a microfluidic device as a size-tunable
separation field for the size-selective separation of micro/nanospheres. The width of the ice …

Open‐tubular nanoelectrochromatography (OT‐NEC): gel‐free separation of single stranded DNAs (ssDNAs) in thermoplastic nanochannels

CA Amarasekara, US Athapattu, C Rathnayaka… - …, 2020 - Wiley Online Library
Electrophoresis or electrochromatography carried out in nanometer columns (width and
depth) offers some attractive benefits compared to microscale columns. These advantages …

Electrokinetic transport properties of deoxynucleotide monophosphates (dNMPs) through thermoplastic nanochannels

C O'Neil, CA Amarasekara… - Analytica chimica …, 2018 - Elsevier
The electrokinetic behavior of molecules in nanochannels (< 100 nm in length) have
generated interest due to the unique transport properties observed that are not seen in …

Electrokinetic identification of ribonucleotide monophosphates (rNMPs) using thermoplastic nanochannels

CA Amarasekara, C Rathnayaka, US Athapattu… - … of Chromatography A, 2021 - Elsevier
With advances in the design and fabrication of nanofluidic devices during the last decade,
there have been a few reports on nucleic acid analysis using nanoscale electrophoresis …

A low-cost fabrication method for high aspect ratio nano-channels by near-field UV exposure and thermal nanoimprinting

W Zhang, Z Yin, L Sun - Journal of Micromechanics and …, 2023 - iopscience.iop.org
A low-cost fabrication method for high aspect ratio nano-channels is proposed in this paper.
The near-field exposure principle based on Fresnel diffraction was analyzed and the silicon …

Fabrication of High Aspect Ratio Nano-Channels by Thermal Nano-Imprinting and Parylene Deposition

K Yang, Z Yin, L Sun - Micromachines, 2023 - mdpi.com
A low-cost method of fabrication of high aspect ratio nano-channels by thermal nano-
imprinting and Parylene deposition is proposed. SU-8 photoresist nano-channels were first …

Electrokinetic motion of single nanoparticles in single PDMS nanochannels

R Peng, D Li - Microfluidics and Nanofluidics, 2017 - Springer
Electrokinetic motion of single nanoparticles in single nanochannels was studied
systematically by image tracking method. A novel method to fabricate PDMS-glass …

Monte Carlo simulation and maximum-likelihood analysis of single-molecule recycling in a nanochannel

B Wang, LM Davis - OSA Continuum, 2021 - opg.optica.org
Prolonged observation of a single molecule in solution using a confocal microscope is
possible by flowing solution through a nanochannel and reversing the flow a fixed delay …