Methods. PubMed, Embase, and clinical trial databases were searched with the key words
“spinal neoplasm,”“spinal instability,”“spinal instability neoplastic score,” and synonyms …

Due to a worldwide increase of cancer incidence and a longer life expectancy of patients
with metastatic cancer, a rise in the incidence of symptomatic vertebral metastases has been …

Objective The Spinal Instability Neoplastic Score (SINS) is widely used to assess
mechanical instability in metastatic spine disease. We sought to identify a cutoff within the …

Mechanical instability is one of the two main indications for surgical intervention in patients
with metastatic spine disease. Since its publication in 2010, the Spinal Instability Neoplastic …

Introduction: Metastatic spinal disease is a source of significant morbidity in patients with
cancer. Recent advancements in adjuvant oncologic therapy has led to increased survival …

Study Design: Narrative review. Objectives: To review the relevant literature regarding
scoring systems for vertebral metastases and quantify their role in contemporary orthopedic …

Introduction: Accurate evaluation of metastasis and life prognosis is essential for selecting a
suitable therapeutic strategy for metastatic spine tumors owing to limitations in treatment …

Radiotherapy has played an important role in the treatment of spinal metastases. One of the
major complications of radiotherapy is vertebral compression fracture (VCF). Although the …

The spine is one of the most common sites of bony metastases, and its involvement leads to
significant patient morbidity. Surgical management in these patients is aimed at improving …

Oncological management of skeletal metastases has changed dramatically in the last few
decades. A significant number of patients survive for many years with their metastases …