Acute myeloid leukemia

H Döhner, DJ Weisdorf… - New England Journal of …, 2015 - Mass Medical Soc
Acute Myeloid Leukemia | New England Journal of Medicine Skip to main content The New
England Journal of Medicine homepage Advanced Search SEARCH SPECIALTIES Cardiology …

Acute lymphoblastic leukemia in children

SP Hunger, CG Mullighan - New England Journal of Medicine, 2015 - Mass Medical Soc
Acute Lymphoblastic Leukemia in Children | New England Journal of Medicine Skip to main
content The New England Journal of Medicine homepage Advanced Search SEARCH …

Acute lymphoblastic leukemia: a comprehensive review and 2017 update

T Terwilliger, M Abdul-Hay - Blood cancer journal, 2017 - nature.com
Acute lymphoblastic leukemia (ALL) is the second most common acute leukemia in adults,
with an incidence of over 6500 cases per year in the United States alone. The hallmark of …

The genomic landscape of pediatric acute lymphoblastic leukemia

SW Brady, KG Roberts, Z Gu, L Shi, S Pounds, D Pei… - Nature …, 2022 - nature.com
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Here, using
whole-genome, exome and transcriptome sequencing of 2,754 childhood patients with ALL …

Acute lymphoblastic leukaemia

F Malard, M Mohty - The Lancet, 2020 - thelancet.com
Acute lymphoblastic leukaemia develops in both children and adults, with a peak incidence
between 1 year and 4 years. Most acute lymphoblastic leukaemia arises in healthy …

The landscape of somatic copy-number alteration across human cancers

R Beroukhim, CH Mermel, D Porter, G Wei… - Nature, 2010 - nature.com
A powerful way to discover key genes with causal roles in oncogenesis is to identify
genomic regions that undergo frequent alteration in human cancers. Here we present high …

[HTML][HTML] Pan-cancer patterns of somatic copy number alteration

TI Zack, SE Schumacher, SL Carter, AD Cherniack… - Nature …, 2013 - nature.com
Determining how somatic copy number alterations (SCNAs) promote cancer is an important
goal. We characterized SCNA patterns in 4,934 cancers from The Cancer Genome Atlas …

Diagnosis and management of acute myeloid leukemia in adults: recommendations from an international expert panel, on behalf of the European LeukemiaNet

H Döhner, EH Estey, S Amadori… - Blood, The Journal …, 2010 - ashpublications.org
In 2003, an international working group last reported on recommendations for diagnosis,
response assessment, and treatment outcomes in acute myeloid leukemia (AML). Since that …

The genomic landscape of pediatric and young adult T-lineage acute lymphoblastic leukemia

Y Liu, J Easton, Y Shao, J Maciaszek, Z Wang… - Nature …, 2017 - nature.com
Genetic alterations that activate NOTCH1 signaling and T cell transcription factors, coupled
with inactivation of the INK4/ARF tumor suppressors, are hallmarks of T-lineage acute …

Activation of proto-oncogenes by disruption of chromosome neighborhoods

D Hnisz, AS Weintraub, DS Day, AL Valton, RO Bak… - Science, 2016 - science.org
Oncogenes are activated through well-known chromosomal alterations such as gene fusion,
translocation, and focal amplification. In light of recent evidence that the control of key genes …