Introduction Photodynamic therapy (PDT) is a two-step treatment involving the
administration of a photosensitive agent followed by its activation at a specific light …

The blood–brain barrier (BBB) is a highly specialized neurovascular unit, initially described
as an intact barrier to prevent toxins, pathogens, and potentially harmful substances from …

Recent advances in maximum safe glioma resection have included the introduction of a host
of visualization techniques to complement intraoperative white-light imaging of tumors …

Background Patients suffering from malignant gliomas have a poor prognosis. For the
surgical treatment of these tumors, 5‐aminolevulinic acid (5‐ALA) has become a new …

Gliomas make up virtually 80% of all lethal primary brain tumors and are categorized based
on their cell of origin. Glioblastoma is an astrocytic tumor that has an inferior prognosis …

Simple Summary Glioblastoma (GBM) is the most common adult brain cancer. Despite
extensive treatment protocols, all glioblastomas are eventually fatal. Photodynamic therapy …

Simple Summary Malignant gliomas are of the deadliest, most hard-to-treat cancers, given
their various characteristics of aggression and infiltration as well as the location of growth …

The blood-brain barrier (BBB) is the one of the most robust physical barriers in the body,
comprised of tight junction (TJ) proteins in brain microvascular endothelial cells. The need …

The blood–brain barrier (BBB) is a selectively permeable membrane that separates the
bloodstream from the brain. While useful for protecting neural tissue from harmful …

With the increase in the aging population, the global number of people with Alzheimer's
disease (AD) progressively increased worldwide. The situation is aggravated by the fact that …