Background No published meta-analyses have assessed efficacy and effectiveness of
licensed influenza vaccines in the USA with sensitive and highly specific diagnostic tests to …

Objectives Summary evidence of influenza vaccine effectiveness (IVE) against hospitalized
influenza is lacking. We conducted a meta-analysis of studies reporting IVE against …

Abstract Background. During the 2012–2013 influenza season, there was cocirculation of
influenza A (H3N2) and 2 influenza B lineage viruses in the United States. Methods. Patients …

Background: The test-negative design is an increasingly popular approach for estimating
vaccine effectiveness (VE) due to its efficiency. This review aims to examine published test …

Adjuvants are substances added to vaccines to improve their immunogenicity. Used for
more than 80 years, aluminum, the first adjuvant in human vaccines, proved insufficient to …

AS03 is an Adjuvant System composed of α-tocopherol, squalene and polysorbate 80 in an
oil-in-water emulsion. In various nonclinical and clinical studies, high levels of antigen …

Background. The predominant strain during the 2013–2014 influenza season was 2009
pandemic influenza A (H1N1) virus (A [H1N1] pdm09). This vaccine-component has …

Background: The test-negative design is a variant of the case–control study being
increasingly used to study influenza vaccine effectiveness (VE). In these studies, patients …

Influenza is a major cause of respiratory disease leading to hospitalization in young
children. However, seasonal trivalent influenza vaccines (TIVs) have been shown to be …

Within the Influenza Monitoring Vaccine Effectiveness in Europe (I-MOVE) project we
conducted a multicentre case-control study in eight European Union (EU) Member States to …