Pericytes of the neurovascular unit: key functions and signaling pathways

MD Sweeney, S Ayyadurai, BV Zlokovic - Nature neuroscience, 2016 - nature.com
Pericytes are vascular mural cells embedded in the basement membrane of blood
microvessels. They extend their processes along capillaries, pre-capillary arterioles and …

Central nervous system pericytes in health and disease

EA Winkler, RD Bell, BV Zlokovic - Nature neuroscience, 2011 - nature.com
Pericytes are uniquely positioned within the neurovascular unit to serve as vital integrators,
coordinators and effectors of many neurovascular functions, including angiogenesis, blood …

Targeting pericytes for therapeutic approaches to neurological disorders

J Cheng, N Korte, R Nortley, H Sethi, Y Tang… - Acta …, 2018 - Springer
Many central nervous system diseases currently lack effective treatment and are often
associated with defects in microvascular function, including a failure to match the energy …

Pathogenesis and prevention of intraventricular hemorrhage

P Ballabh - Clinics in perinatology, 2013 - pmc.ncbi.nlm.nih.gov
Intraventricular hemorrhage (IVH) is a major neurological complication of prematurity.
Pathogenesis of intraventricular hemorrhage is attributed to intrinsic fragility of germinal …

Vascular remodeling after ischemic stroke: mechanisms and therapeutic potentials

J Liu, Y Wang, Y Akamatsu, CC Lee, RA Stetler… - Progress in …, 2014 - Elsevier
The brain vasculature has been increasingly recognized as a key player that directs brain
development, regulates homeostasis, and contributes to pathological processes. Following …

Cranial ultrasound findings in preterm germinal matrix haemorrhage, sequelae and outcome

A Parodi, P Govaert, S Horsch, MC Bravo… - Pediatric …, 2020 - nature.com
Germinal matrix-intraventricular haemorrhage (GMH-IVH), periventricular haemorrhagic
infarction (PHI) and its complication, post-haemorrhagic ventricular dilatation (PHVD), are …

Blood-brain barrier integrity in the pathogenesis of Alzheimer's disease

Z Huang, LW Wong, Y Su, X Huang, N Wang… - Frontiers in …, 2020 - Elsevier
The blood–brain barrier (BBB) tightly controls the molecular exchange between the brain
parenchyma and blood. Accumulated evidence from transgenic animal Alzheimer's disease …

Germinal Matrix‐Intraventricular Hemorrhage: A Tale of Preterm Infants

WI Egesa, S Odoch, RJ Odong… - … Journal of pediatrics, 2021 - Wiley Online Library
Germinal matrix‐intraventricular hemorrhage (GM‐IVH) is a common intracranial
complication in preterm infants, especially those born before 32 weeks of gestation and very …

The CNS microvascular pericyte: pericyte-astrocyte crosstalk in the regulation of tissue survival

D Bonkowski, V Katyshev, RD Balabanov… - Fluids and Barriers of …, 2011 - Springer
Abstract The French scientist Charles Benjamin Rouget identified the pericyte nearly 140
years ago. Since that time the role of the pericyte in vascular function has been difficult to …

Vulnerability of the develo** brain to hypoxic-ischemic damage: contribution of the cerebral vasculature to injury and repair?

AA Baburamani, CJ Ek, DW Walker… - Frontiers in …, 2012 - frontiersin.org
As clinicians attempt to understand the underlying reasons for the vulnerability of different
regions of the develo** brain to injury, it is apparent that little is known as to how hypoxia …