Nanoformulations in the treatment of lung cancer: current status and clinical potential

MA Younis, MA Alsogaihi, AAH Abdellatif… - Drug Development …, 2024 - Taylor & Francis
Objective Recent developments in nanotechnology have regained hope in enabling the
eradication of lung cancer, while overcoming the drawbacks of the classic therapeutics …

Understanding Gene Involvement in Hepatocellular Carcinoma: Implications for Gene Therapy and Personalized Medicine

MA Younis, H Harashima - Pharmacogenomics and Personalized …, 2024 - Taylor & Francis
Hepatocellular carcinoma (HCC) is the dominant type of liver cancers and is one of the
deadliest health threats globally. The conventional therapeutic options for HCC are …

MCT4 knockdown by tumor microenvironment-responsive nanoparticles remodels the cytokine profile and eradicates aggressive breast cancer cells

AAH Abdellatif, A Bouazzaoui, HM Tawfeek… - Colloids and Surfaces B …, 2024 - Elsevier
Breast cancer is a wide-spread threat to the women's health. The drawbacks of conventional
treatments necessitate the development of alternative strategies, where gene therapy has …

Clinical translation of silver nanoparticles into the market

MA Younis - Silver Nanoparticles for Drug Delivery, 2024 - Elsevier
Recently, there has been a growing interest in silver nanoparticles (AgNPs) and their
biomedical applications. Nevertheless, the clinical translation of such a promising …

Comprehensive review for non-coding RNAs: From mechanisms to therapeutic applications

YJ Zhang, L Zhan, X Jiang, X Tang - Biochemical Pharmacology, 2024 - Elsevier
Non-coding RNAs (ncRNAs) are an assorted collection of transcripts that are not translated
into proteins. Since their discovery, ncRNAs have gained prominence as crucial regulators …

Targeted Nanoparticles: the Smart Way for the Treatment of Colorectal Cancer

AAH Abdellatif, AS Alshubrumi, MA Younis - AAPS PharmSciTech, 2024 - Springer
Colorectal cancer (CRC) is a widespread cancer that starts in the digestive tract. It is the third
most common cause of cancer deaths around the world. The World Health Organization …

The dysregulated autophagy in osteoarthritis: Revisiting molecular profile

L Liu, J Wang, W Shi, H Gao, L Liu - Progress in Biophysics and …, 2024 - Elsevier
The risk factors of osteoarthritis (OA) are different and obesity, lifestyle, inflammation, cell
death mechanisms and diabetes mellitus are among them. The changes in the biological …

Theoretical perspectives and clinical applications of non-coding RNA in lung cancer metastasis: a systematic review

J Yang, Y Luo, Z Yao, Z Wang, K Jiang - Discover Oncology, 2025 - Springer
Lung cancer is one of the deadliest malignancies worldwide, with distant metastasis being a
major cause of death. However, the specific mechanisms of lung cancer metastasis remain …

Exploring the prognostic analysis of autophagy and tumor microenvironment based on monocyte cells in lung cancer

B Tao, Z Wang, D **e, H Cui, B Zhao, J Li… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
A deep understanding of the biological mechanisms of lung cancer offers more precise
treatment options for patients. In our study, we integrated data from the Gene Expression …