Radical C–H functionalization represents a useful means of streamlining synthetic routes by
avoiding substrate preactivation and allowing access to target molecules in fewer steps. The …

In recent years, metalloenzymes‐mediated highly selective oxidations of organic substrates
under mild conditions have been inspiration for develo** synthetic bioinspired catalyst …

The development of catalytic systems capable of oxygenating unactivated C–H bonds with
excellent site-selectivity and functional group tolerance under mild conditions remains a …

Chiral oxygenated aliphatic moieties are recurrent in biological and pharmaceutically
relevant molecules and constitute one of the most versatile types of functionalities for further …

Designing catalytic approaches to deliberate and selective C–H activation was listed by
Bergman among the “Holy Grails” of synthetic chemistry in 1995, and continues to be a hot …

Enantioselective C–H oxidation is a standing chemical challenge foreseen as a powerful
tool to transform readily available organic molecules into precious oxygenated building …

The C (sp3)–H bond oxygenation of a variety of cyclopropane containing hydrocarbons with
hydrogen peroxide catalyzed by manganese complexes containing aminopyridine …

Methyl groups are ubiquitous in natural products and biologically active compounds, but
methods for their selective transformation in such structures are limited. For example …

Spirocyclobutane derivatives have gained significant attention in drug discovery programs
due to their broad spectrum of biological activities and clinical applications. Ring-strain in …

Herein, we report the direct selective C–H lactonization of fatty acids (C5–C16), catalyzed by
manganese (II) complexes bearing bis-amino-bis-pyridine ligands. The catalyst system uses …