Nutrition profoundly shapes immunity and inflammation across the lifespan of mammals,
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …

The human gut microbiome vastly extends the set of metabolic reactions catalysed by our
own cells, with far-reaching consequences for host health and disease. However, our …

While food is essential for survival, it can also cause a variety of harmful effects, ranging from
intolerance to specific nutrients to celiac disease and food allergies. In addition to nutrients …

The human gut microbiome is highly personal. However, the contribution of gut physiology
and environment to variations in the gut microbiome remains understudied. Here we …

Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

The human microbiome and its metabolic output play an important role in sha** human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …

The repertoire of modifications to bile acids and related steroidal lipids by host and microbial
metabolism remains incompletely characterized. To address this knowledge gap, we …

Highlights•Many environmental biotechnologies are driven by diverse microbiomes.•Current
environmental process models do not account for physiological diversity.•New modeling …

The gut microbiota has been found to play an important role in the progression of metabolic
dysfunction-associated steatohepatitis (MASH), but the mechanisms have not been …

Advances in genome engineering and associated technologies have reinvigorated natural
products research. Here we highlight the latest developments in the field across the discover …