Bile acids regulate nutrient absorption and mitochondrial function, they establish and
maintain gut microbial community composition and mediate inflammation, and they serve as …

Nutrition profoundly shapes immunity and inflammation across the lifespan of mammals,
from pre-and post-natal periods to later life. Emerging insights into diet-microbiota …

The gut microbiota has been found to play an important role in the progression of metabolic
dysfunction-associated steatohepatitis (MASH), but the mechanisms have not been …

The repertoire of modifications to bile acids and related steroidal lipids by host and microbial
metabolism remains incompletely characterized. To address this knowledge gap, we …

One of the key modes of microbial metabolism occurring in the gut microbiome is
fermentation. This energy-yielding process transforms common macromolecules like …

The human gut microbiome vastly extends the set of metabolic reactions catalysed by our
own cells, with far-reaching consequences for host health and disease. However, our …

Unknown forever chemicals like per-and polyfluoroalkyl substances (PFASs) are difficult to
identify. Current platforms designed for metabolites and natural products cannot capture the …

In the relentless battle for human health, the proliferation of antibiotic‐resistant bacteria has
emerged as an impending catastrophe of unprecedented magnitude, potentially driving …

While food is essential for survival, it can also cause a variety of harmful effects, ranging from
intolerance to specific nutrients to celiac disease and food allergies. In addition to nutrients …

The human microbiome and its metabolic output play an important role in sha** human
health and disease. The host-microbe crosstalk is often characterised using metabolomics …