A synergetic turn in cognitive neuroscience of brain diseases

A Ibanez, ML Kringelbach, G Deco - Trends in Cognitive Sciences, 2024 - cell.com
Despite significant improvements in our understanding of brain diseases, many barriers
remain. Cognitive neuroscience faces four major challenges: complex structure–function …

[HTML][HTML] Neurobiological mechanisms for language, symbols and concepts: clues from brain-constrained deep neural networks

F Pulvermüller - Progress in Neurobiology, 2023 - Elsevier
Neural networks are successfully used to imitate and model cognitive processes. However,
to provide clues about the neurobiological mechanisms enabling human cognition, these …

Whole-brain turbulent dynamics predict responsiveness to pharmacological treatment in major depressive disorder

A Escrichs, Y Sanz Perl, PM Fisher… - Molecular …, 2024 - nature.com
Depression is a multifactorial clinical syndrome with a low pharmacological treatment
response rate. Therefore, identifying predictors of treatment response capable of providing …

Human brain dynamics are shaped by rare long-range connections over and above cortical geometry

J Vohryzek, Y Sanz-Perl, ML Kringelbach… - Proceedings of the …, 2025 - pnas.org
A fundamental topological principle is that the container always shapes the content. In
neuroscience, this translates into how the brain anatomy shapes brain dynamics. From …

Computational modelling in disorders of consciousness: Closing the gap towards personalised models for restoring consciousness

AI Luppi, J Cabral, R Cofre, PAM Mediano, FE Rosas… - NeuroImage, 2023 - Elsevier
Disorders of consciousness are complex conditions characterised by persistent loss of
responsiveness due to brain injury. They present diagnostic challenges and limited options …

The digital twin brain: A bridge between biological and artificial intelligence

H **ong, C Chu, L Fan, M Song, J Zhang, Y Ma… - Intelligent …, 2023 - spj.science.org
In recent years, advances in neuroscience and artificial intelligence have paved the way for
unprecedented opportunities to understand the complexity of the brain and its emulation …

Brain dynamics predictive of response to psilocybin for treatment-resistant depression

J Vohryzek, J Cabral, LD Lord… - Brain …, 2024 - academic.oup.com
Psilocybin therapy for depression has started to show promise, yet the underlying causal
mechanisms are not currently known. Here, we leveraged the differential outcome in …

[HTML][HTML] The algorithmic agent perspective and computational neuropsychiatry: From etiology to advanced therapy in major depressive disorder

G Ruffini, F Castaldo, E Lopez-Sola, R Sanchez-Todo… - Entropy, 2024 - mdpi.com
Major Depressive Disorder (MDD) is a complex, heterogeneous condition affecting millions
worldwide. Computational neuropsychiatry offers potential breakthroughs through the …

Whole brain modelling for simulating pharmacological interventions on patients with disorders of consciousness

I Mindlin, R Herzog, L Belloli, D Manasova… - Communications …, 2024 - nature.com
Disorders of consciousness (DoC) represent a challenging and complex group of
neurological conditions characterised by profound disturbances in consciousness. The …

The unique neural signature of your trip: Functional connectome fingerprints of subjective psilocybin experience

HM Tolle, JC Farah, P Mallaroni, NL Mason… - Network …, 2024 - direct.mit.edu
The emerging neuroscientific frontier of brain fingerprinting has recently established that
human functional connectomes (FCs) exhibit fingerprint-like idiosyncratic features, which …