Droplet-based microfluidics in biomedical applications

L Amirifar, M Besanjideh, R Nasiri, A Shamloo… - …, 2022 - iopscience.iop.org
Droplet-based microfluidic systems have been employed to manipulate discrete fluid
volumes with immiscible phases. Creating the fluid droplets at microscale has led to a …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Microfluidic hydrodynamic focusing for synthesis of nanomaterials

M Lu, A Ozcelik, CL Grigsby, Y Zhao, F Guo, KW Leong… - Nano Today, 2016 - Elsevier
Microfluidics expands the synthetic space such as heat transfer, mass transport, and reagent
consumption to conditions not easily achievable in conventional batch processes …

Advances in microfluidic PCR for point-of-care infectious disease diagnostics

S Park, Y Zhang, S Lin, TH Wang, S Yang - Biotechnology advances, 2011 - Elsevier
Global burdens from existing or emerging infectious diseases emphasize the need for point-
of-care (POC) diagnostics to enhance timely recognition and intervention. Molecular …

Dielectrophoresis: Developments and applications from 2010 to 2020

B Sarno, D Heineck, MJ Heller, SD Ibsen - Electrophoresis, 2021 - Wiley Online Library
The 20th century has seen tremendous innovation of dielectrophoresis (DEP) technologies,
with applications being developed in areas ranging from industrial processing to micro‐and …

Continuous dielectrophoretic bacterial separation and concentration from physiological media of high conductivity

S Park, Y Zhang, TH Wang, S Yang - Lab on a Chip, 2011 - pubs.rsc.org
Biological sample processing involves purifying target analytes from various sample
matrices and concentrating them to a small volume from a large volume of crude sample …

Magnetically actuated droplet manipulation and its potential biomedical applications

G Huang, M Li, Q Yang, Y Li, H Liu… - ACS applied materials …, 2017 - ACS Publications
Droplet manipulation has found broad applications in various engineering and biomedical
fields, such as biochemistry, microfluidic systems, drug delivery, and tissue engineering …

Diagnosis of bloodstream infections: an evolution of technologies towards accurate and rapid identification and antibiotic susceptibility testing

KC Tjandra, N Ram-Mohan, R Abe, MM Hashemi… - Antibiotics, 2022 - mdpi.com
Bloodstream infections (BSI) are a leading cause of death worldwide. The lack of timely and
reliable diagnostic practices is an ongoing issue for managing BSI. The current gold …

A surface topography assisted droplet manipulation platform for biomarker detection and pathogen identification

Y Zhang, S Park, K Liu, J Tsuan, S Yang, TH Wang - Lab on a Chip, 2011 - pubs.rsc.org
This paper reports a droplet microfluidic, sample-to-answer platform for the detection of
disease biomarkers and infectious pathogens using crude biosamples. The platform …

Miniaturized nucleic acid amplification systems for rapid and point-of-care diagnostics: a review

F Ahmad, SA Hashsham - Analytica chimica acta, 2012 - Elsevier
Point-of-care (POC) genetic diagnostics critically depends on miniaturization and integration
of sample processing, nucleic acid amplification, and detection systems. Polymerase chain …