Changing the strength of connections between neurons is widely assumed to be the
mechanism by which memory traces are encoded and stored in the central nervous system …

Synaptic plasticity is a key component of the learning machinery in the brain. It is vital that
such plasticity be tightly regulated so that it occurs to the proper extent at the proper time …

Enhanced glutamatergic transmission in the nucleus accumbens (NAc), a region critical for
reward and motivation, has been implicated in the pathophysiology of depression; however …

Aging is associated with specific impairments of learning and memory, some of which are
similar to those caused by hippocampal damage. Studies of the effects of aging on …

Thirty years have passed since the publication of Elie Bienenstock, Leon Cooper and Paul
Munro's' Theory for the development of neuron selectivity: orientation specificity and …

The age of an experimental animal can be a critical variable, yet age matters are often
overlooked within neuroscience. Many studies make use of young animals, without …

Since its commercial advent in 1985, transcranial magnetic stimulation (TMS), a technique
for stimulating neurons in the cerebral cortex through the scalp, safely and with minimal …

Behavioural experience (eg chronic stress, environmental enrichment) can have long‐
lasting effects on cognitive functions. Because activity‐dependent persistent changes in …

Experiments were conducted using hippocampal slices in vitro to compare two accounts of
the mechanisms by which input-specific protein synthesis-dependent long-term potentiation …

A novel Hebbian stimulation paradigm was employed to examine physiological correlates of
motor memory formation in humans. Repetitive pairing of median nerve stimulation with …