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An official ATS statement: hepatotoxicity of antituberculosis therapy
JJ Saukkonen, DL Cohn, RM Jasmer… - American journal of …, 2006 - atsjournals.org
Drug-induced liver injury (DILI) is a problem of increasing significance, but has been a long-
standing concern in the treatment of tuberculosis (TB) infection. The liver has a central role …
standing concern in the treatment of tuberculosis (TB) infection. The liver has a central role …
MRGPRX2 and adverse drug reactions
BD McNeil - Frontiers in immunology, 2021 - frontiersin.org
Many adverse reactions to therapeutic drugs appear to be allergic in nature, and are thought
to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug …
to be triggered by patient-specific Immunoglobulin E (IgE) antibodies that recognize the drug …
[PDF][PDF] Drug allergy: a 2022 practice parameter update
DA Khan, A Banerji, KG Blumenthal, EJ Phillips… - Journal of Allergy and …, 2022 - Elsevier
Resolving conflict of interest The Joint Task Force on Practice Parameters (JTFPP) is
committed to ensuring that all guidelines are based on the best scientific evidence at the …
committed to ensuring that all guidelines are based on the best scientific evidence at the …
Antimicrobial safety: focus on fluoroquinolones
RC Owens Jr, PG Ambrose - Clinical infectious diseases, 2005 - academic.oup.com
Background/purpose. Infrequent toxicities associated with certain drugs and drug classes
have recently gained much attention from different health-care perspectives. To protect the …
have recently gained much attention from different health-care perspectives. To protect the …
[HTML][HTML] Quinolones in 2005: an update
F Van Bambeke, JM Michot, J Van Eldere… - Clinical Microbiology …, 2005 - Elsevier
Quinolones are one of the largest classes of antimicrobial agents used worldwide. This
review considers the quinolones that are available currently and used widely in Europe …
review considers the quinolones that are available currently and used widely in Europe …
Hepatic safety of antibiotics used in primary care
RJ Andrade, PM Tulkens - Journal of Antimicrobial …, 2011 - academic.oup.com
Antibiotics used by general practitioners frequently appear in adverse-event reports of drug-
induced hepatotoxicity. Most cases are idiosyncratic (the adverse reaction cannot be …
induced hepatotoxicity. Most cases are idiosyncratic (the adverse reaction cannot be …
Substitution of moxifloxacin for isoniazid during intensive phase treatment of pulmonary tuberculosis
SE Dorman, JL Johnson, S Goldberg… - American journal of …, 2009 - atsjournals.org
Rationale: Moxifloxacin has potent activity against Mycobacterium tuberculosis in vitro and
in a mouse model of antituberculosis (TB) chemotherapy, but data regarding its activity in …
in a mouse model of antituberculosis (TB) chemotherapy, but data regarding its activity in …
Safety considerations of fluoroquinolones in the elderly: an update
R Stahlmann, H Lode - Drugs & aging, 2010 - Springer
The fluoroquinolones ciprofloxacin, levofloxacin, moxifloxacin and gemifloxacin are widely
used for the treatment of various types of bacterial infections. Overall, these antibacterial …
used for the treatment of various types of bacterial infections. Overall, these antibacterial …
Safety profile of the fluoroquinolones: focus on levofloxacin
HH Liu - Drug Safety, 2010 - Springer
The fluoroquinolone class of antibacterial agents are among the most frequently prescribed
drugs, with utility in a broad range of bacterial infections. Although very useful agents, the …
drugs, with utility in a broad range of bacterial infections. Although very useful agents, the …
Allergenic and mas-related G protein-coupled receptor X2-activating properties of drugs: resolving the two
V Sabato, DG Ebo, MLM Van Der Poorten… - The Journal of Allergy …, 2023 - Elsevier
Since the seminal description implicating occupation of the Mas-related G protein-coupled
receptor X2 (MRGPRX2) in mast cell (MC) degranulation by drugs, many investigations …
receptor X2 (MRGPRX2) in mast cell (MC) degranulation by drugs, many investigations …