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Lizards and the enzootic cycle of Borrelia burgdorferi sensu lato
Emerging and re‐emerging pathogens often stem from zoonotic origins, cycling between
humans and animals, and are frequently vectored and maintained by hematophagous …
humans and animals, and are frequently vectored and maintained by hematophagous …
Evolutionary genetics of Borrelia
The genus Borrelia consists of evolutionarily and genetically diverse bacterial species that
cause a variety of diseases in humans and domestic animals. These vector-borne …
cause a variety of diseases in humans and domestic animals. These vector-borne …
Host tropism determination by convergent evolution of immunological evasion in the Lyme disease system
Pathogens possess the ability to adapt and survive in some host species but not in others–
an ecological trait known as host tropism. Transmitted through ticks and carried mainly by …
an ecological trait known as host tropism. Transmitted through ticks and carried mainly by …
Borrelia burgdorferi strain and host sex influence pathogen prevalence and abundance in the tissues of a laboratory rodent host
Experimental infections with different pathogen strains give insight into pathogen life history
traits. The purpose of the present study was to compare variation in tissue infection …
traits. The purpose of the present study was to compare variation in tissue infection …
Competition between strains of Borrelia afzelii in the host tissues and consequences for transmission to ticks
D Genné, M Rossel, A Sarr, F Battilotti, O Rais… - The ISME …, 2021 - academic.oup.com
Pathogen species often consist of genetically distinct strains, which can establish mixed
infections or coinfections in the host. In coinfections, interactions between pathogen strains …
infections or coinfections in the host. In coinfections, interactions between pathogen strains …
Tick-to-host transmission differs between Borrelia afzelii strains
D Genné, W Jiricka, A Sarr… - Microbiology Spectrum, 2023 - journals.asm.org
Many vector-borne pathogens establish multiple-strain infections in the vertebrate host and
the arthropod vector. Multiple-strain infections in the host influence strain acquisition by …
the arthropod vector. Multiple-strain infections in the host influence strain acquisition by …
Maternal antibodies provide bank voles with strain-specific protection against infection by the Lyme disease pathogen
A Gomez-Chamorro, V Heinrich, A Sarr… - Applied and …, 2019 - journals.asm.org
Multistrain microbial pathogens often induce strain-specific antibody responses in their
vertebrate hosts. Mothers can transmit antibodies to their offspring, which can provide short …
vertebrate hosts. Mothers can transmit antibodies to their offspring, which can provide short …
Clobetasol increases the abundance of Borrelia burgdorferi in the skin 70 times more in male mice compared to female mice
Lyme borreliosis is caused by the spirochete Borrelia burgdorferi and is transmitted among
vertebrate hosts by Ixodes scapularis ticks in eastern North America. Treatment with topical …
vertebrate hosts by Ixodes scapularis ticks in eastern North America. Treatment with topical …
Infection with Borrelia afzelii and manipulation of the egg surface microbiota have no effect on the fitness of immature Ixodes ricinus ticks
G Hurry, E Maluenda, A Sarr, A Belli, PT Hamilton… - Scientific Reports, 2021 - nature.com
Arthropod vectors carry vector-borne pathogens that cause infectious disease in vertebrate
hosts, and arthropod-associated microbiota, which consists of non-pathogenic …
hosts, and arthropod-associated microbiota, which consists of non-pathogenic …
Evolutionary trade-offs constraining the MHC gene expansion: beyond simple TCR depletion model
The immune system is as much shaped by the pressure of pathogens as it is by evolutionary
trade-offs that constrain its structure and function. A perfect example comes from the major …
trade-offs that constrain its structure and function. A perfect example comes from the major …