Long noncoding RNAs in the pathogenesis of insulin resistance

W Yang, Y Lyu, R **ang, J Yang - International journal of molecular …, 2022 - mdpi.com
Insulin resistance (IR), designated as the blunted response of insulin target tissues to
physiological level of insulin, plays crucial roles in the development and progression of …

Endocrine nuclear receptors and long non-coding RNAs reciprocal regulation in cancer

M Cantile, M Cerrone, M Di Bonito… - International …, 2023 - spandidos-publications.com
Nuclear receptors (NRs) are transcriptional regulators involved in different aspects of normal
cell physiology. Their deregulation is associated with aberrant expression, gene mutations …

[HTML][HTML] Combined High—Throughput Proteomics and Random Forest Machine-Learning Approach Differentiates and Classifies Metabolic, Immune, Signaling and …

C Contini, B Manconi, A Olianas, G Guadalupi… - Cells, 2024 - mdpi.com
Colorectal cancer (CRC) is a frequent, worldwide tumor described for its huge complexity,
including inter-/intra-heterogeneity and tumor microenvironment (TME) variability. Intra …

Identification of lncRNAs associated with the progression of acute lymphoblastic leukemia using a competing endogenous RNAs network

S Nekoeian, T Rostami, A Norouzy… - Oncology …, 2023 - pmc.ncbi.nlm.nih.gov
Acute lymphoblastic leukemia (ALL) is a malignancy of bone marrow lymphoid precursors.
Despite effective treatments, the causes of its progression or recurrence are still unknown …

Unlocking the potential of Escherichia coli K-12: A novel approach for malignancy reduction in colorectal cancer through gene expression modulation

Z Rohani, H Sazegar, E Rahimi - Gene, 2024 - Elsevier
Studies have noted the association between Escherichia coli K-12 (E. coli K-12) and the
reduction of malignancy in colorectal cancer (CRC). However, the molecular mechanisms …

Identification of genes with high heterogeneity of expression as a predictor of different prognosis and therapeutic responses in colorectal cancer: a challenge and a …

E Salehitabar, M Mahdevar, A Valipour Motlagh… - Cancer cell …, 2022 - Springer
Background Molecular heterogeneity is one of the most important concerns in colorectal
cancer (CRC), which results in a wide range of therapy responses and patient prognosis …

Diagnostic and therapeutic potential of LINC01929 as an oncogenic LncRNA in human cancers

N Salimian, M Peymani, K Ghaedi, S Mirzaei… - … -Research and Practice, 2023 - Elsevier
Recent findings have shown the significant role of long non-coding RNAs in the
pathogenesis of various cancers. In this regard, the variation in the expression of …

Prognostic significance of CHCHD2P9 and ZNF204P in breast cancer: exploring their expression patterns and associations with malignancy-related genes

M Rastegari, H Sazegar, A Doosti - Molecular Biology Reports, 2024 - Springer
Abstract Background Non-coding RNAs (ncRNAs) have a crucial impact on diverse cellular
processes, influencing the progression of breast cancer (BC). The objective of this study was …

[PDF][PDF] Association of MIR4435-2HG Expression with TP53 Mutation, Estrogen Receptor Activity, and Poor Prognosis in Breast Cancer.

M Bayat, H Nazem, M Fazilati, H Hejazi… - Jentashapir Journal of …, 2023 - sid.ir
Background: The roles of many long noncoding RNAs (lncRNAs) in breast cancer (BC) are
unclear, and the medications that affect them have attracted less attention. Objectives: This …

[PDF][PDF] Bioinformatics molecular analysis of prognostic-related genes and drug sensitivity and resistance in head and neck squamous cell carcinomas

RO Saleh, YF Mustafa, B Abdullaev, AT Jalil… - 2022 - scholar.archive.org
One of the most heterogeneous collections of malignancies probably is head and neck
cancers that in this study, we focus on the head and neck squamous cell carcinomas …