Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the
world. Although considerable progress has been made in the diagnosis, treatment and …

Pulmonary hypertension (PH) is a progressive disease that arises from multiple etiologies
and ultimately leads to right heart failure as the predominant cause of morbidity and …

Blood and lymphatic vessels are lined by endothelial cells which constantly interact with
their luminal and abluminal extracellular environments. These interactions confer physical …

The vascular adventitia acts as a biological processing center for the retrieval, integration,
storage, and release of key regulators of vessel wall function. It is the most complex …

Rationale: Premature birth affects 10% of live births in the United States and is associated
with alveolar simplification and altered pulmonary microvascular development. However …

Pulmonary hypertension (PH) is a deadly vascular disease with enigmatic molecular origins.
We found that vascular extracellular matrix (ECM) remodeling and stiffening are early and …

Pulmonary artery pulsatility index (PAPi) is a haemodynamic parameter that is derived from
right atrial and pulmonary artery pulse pressures. A number of reports have described the …

The pulmonary circulation is a low-resistance, low-pressure, and high-compliance system
that allows the lungs to receive the entire cardiac output. Pulmonary arterial pressure is a …

The normal pulmonary circulation is a low-pressure, high-compliance system. Pulmonary
arterial compliance decreases in the presence of pulmonary hypertension because of …

Objectives: The aim of the present study was to elucidate right ventricular (RV) function and
structure in patients with chronic obstructive pulmonary disease (COPD) without pulmonary …