Animal models of human cardiovascular disease, heart failure and hypertrophy

G Hasenfuss - Cardiovascular research, 1998 - academic.oup.com
The progress made in our understanding of the pathophysiology and treatment of
congestive heart failure (CHF) would not have been possible without a number of animal …

Factors controlling cardiac myosin-isoform shift during hypertrophy and heart failure

MP Gupta - Journal of molecular and cellular cardiology, 2007 - Elsevier
Myosin is a molecular motor, which interacts with actin to convert the energy from ATP
hydrolysis into mechanical work. In cardiac myocytes, two myosin isoforms are expressed …

Alpha and beta myosin isoforms and human atrial and ventricular contraction

J Walklate, C Ferrantini, CA Johnson, C Tesi… - Cellular and Molecular …, 2021 - Springer
Human atrial and ventricular contractions have distinct mechanical characteristics including
speed of contraction, volume of blood delivered and the range of pressure generated …

Characterization of cardiac hypertrophy and heart failure due to volume overload in the rat

XI Wang, B Ren, S Liu, E Sentex… - Journal of applied …, 2003 - journals.physiology.org
Alterations in general characteristics and morphology of the heart, as well as changes in
hemodynamics, myosin heavy chain isoforms, and β-adrenoceptor responsiveness, were …

Cardiac adaptations to chronic exercise

TF Schaible, J Scheuer - Progress in cardiovascular diseases, 1985 - Elsevier
HERE IS INCREASING evidence that prolonged physical conditioning may lead to a lower
incidence of death from cardiovascular diseases. 1 This may be due in part to the potential …

Alterations of adenylyl cyclase and G proteins in aortocaval shunt-induced heart failure

X Wang, E Sentex, D Chapman… - American Journal of …, 2004 - journals.physiology.org
Unlike most other experimental models of congestive heart failure, the volume overload
model induced by aortocaval shunt (AVS) in rats was found to exhibit enhanced β …

[HTML][HTML] The effects of a 10-week water aerobic exercise on the resting blood pressure in patients with essential hypertension

AV Farahani, MA Mansournia, H Asheri… - Asian journal of …, 2010 - ncbi.nlm.nih.gov
Purpose To investigate the effects of a 10-week water aerobic exercise on the resting blood
pressure in patients with stage 1 or 2 hypertension referring to Tehran University Clinics …

Transmural progression of morphologic changes during ischemic contracture and reperfusion in the normal and hypertrophied rat heart.

PG Anderson, SP Bishop… - The American journal of …, 1987 - ncbi.nlm.nih.gov
The purpose of this study was to compare the functional and morphologic changes that
occur during ischemic contracture and reperfusion in the normal and hypertrophied heart …

Myocardial mechanical and myosin isoenzyme alterations in streptozotocin-diabetic rats

N TAKEDA, I NAKAMURA, T HATANAKA… - Japanese heart …, 1988 - jstage.jst.go.jp
Fifteen week old male Wistar rats (n= 7) were made diabetic by intravenous injection of
streptozotocin(50mg/kg). Age-matched, untreated male Wistar rats (n= 9) served as controls …

Differential effect of physical exercise routines on ventricular myosin and peripheral catecholamine stores in normotensive and spontaneously hypertensive rats.

H Rupp - Circulation research, 1989 - Am Heart Assoc
The influence of the adrenergic system on the population of ventricular myosin isoenzymes
under physiological conditions was assessed by subjection of normotensive and …