[HTML][HTML] Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

J Lloyd-Price, C Arze, AN Ananthakrishnan… - Nature, 2019 - nature.com
Inflammatory bowel diseases, which include Crohn's disease and ulcerative colitis, affect
several million individuals worldwide. Crohn's disease and ulcerative colitis are complex …

Fungal diversity revisited: 2.2 to 3.8 million species

DL Hawksworth, R Lücking - Microbiology spectrum, 2017 - Am Soc Microbiol
The question of how many species of Fungi there are has occasioned much speculation,
with figures mostly posited from around half a million to 10 million, and in one extreme case …

Sensitive protein alignments at tree-of-life scale using DIAMOND

B Buchfink, K Reuter, HG Drost - Nature methods, 2021 - nature.com
We are at the beginning of a genomic revolution in which all known species are planned to
be sequenced. Accessing such data for comparative analyses is crucial in this new age of …

[HTML][HTML] Tumor-resident intracellular microbiota promotes metastatic colonization in breast cancer

A Fu, B Yao, T Dong, Y Chen, J Yao, Y Liu, H Li, H Bai… - Cell, 2022 - cell.com
Tumor-resident intracellular microbiota is an emerging tumor component that has been
documented for a variety of cancer types with unclear biological functions. Here, we …

Illuminating protein space with a programmable generative model

JB Ingraham, M Baranov, Z Costello, KW Barber… - Nature, 2023 - nature.com
Three billion years of evolution has produced a tremendous diversity of protein molecules,
but the full potential of proteins is likely to be much greater. Accessing this potential has …

Optimizing taxonomic classification of marker-gene amplicon sequences with QIIME 2's q2-feature-classifier plugin

NA Bokulich, BD Kaehler, JR Rideout, M Dillon… - Microbiome, 2018 - Springer
Background Taxonomic classification of marker-gene sequences is an important step in
microbiome analysis. Results We present q2-feature-classifier (https://github. com/qiime2/q2 …

Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike

L Liu, P Wang, MS Nair, J Yu, M Rapp, Q Wang, Y Luo… - Nature, 2020 - nature.com
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic continues,
with devasting consequences for human lives and the global economy,. The discovery and …

The UNITE database for molecular identification of fungi: handling dark taxa and parallel taxonomic classifications

RH Nilsson, KH Larsson, AFS Taylor… - Nucleic acids …, 2019 - academic.oup.com
Abstract UNITE (https://unite. ut. ee/) is a web-based database and sequence management
environment for the molecular identification of fungi. It targets the formal fungal barcode—the …

Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients

V Gopalakrishnan, CN Spencer, L Nezi, A Reuben… - Science, 2018 - science.org
Preclinical mouse models suggest that the gut microbiome modulates tumor response to
checkpoint blockade immunotherapy; however, this has not been well-characterized in …

Introducing EzBioCloud: a taxonomically united database of 16S rRNA gene sequences and whole-genome assemblies

SH Yoon, SM Ha, S Kwon, J Lim… - … of systematic and …, 2017 - microbiologyresearch.org
The recent advent of DNA sequencing technologies facilitates the use of genome
sequencing data that provide means for more informative and precise classification and …