Distinct evolution of SARS-CoV-2 Omicron XBB and BA. 2.86/JN. 1 lineages combining increased fitness and antibody evasion

D Planas, I Staropoli, V Michel, F Lemoine… - Nature …, 2024 - nature.com
The unceasing circulation of SARS-CoV-2 leads to the continuous emergence of novel viral
sublineages. Here, we isolate and characterize XBB. 1, XBB. 1.5, XBB. 1.9. 1, XBB. 1.16. 1 …

[HTML][HTML] Humoral immune escape by current SARS-CoV-2 variants BA. 2.86 and JN. 1, December 2023

LM Jeworowski, B Mühlemann, F Walper… - …, 2024 - eurosurveillance.org
Variant BA. 2.86 and its descendant, JN. 1, of SARS-CoV-2 are rising in incidence across
Europe and globally. We isolated recent JN. 1, BA. 2.86, EG. 5, XBB. 1.5 and earlier variants …

Short-term effectiveness of the XBB. 1.5 updated COVID-19 vaccine against hospitalisation in Denmark: a national cohort study

CH Hansen, IR Moustsen-Helms… - The Lancet Infectious …, 2024 - thelancet.com
The vaccines currently form part of the national immunisation programmes in many countries
including Denmark. Both vaccines incorporate a monovalent component designed to target …

Safety and immunogenicity of the monovalent omicron XBB. 1.5-adapted BNT162b2 COVID-19 vaccine in individuals≥ 12 years old: a phase 2/3 trial

J Gayed, O Diya, FS Lowry, X Xu, V Bangad, F Mensa… - Vaccines, 2024 - mdpi.com
Vaccination remains an important mitigation tool against COVID-19. We report 1-month
safety and preliminary immunogenicity data from a substudy of an ongoing, open-label …

Antigenic sin and multiple breakthrough infections drive converging evolution of COVID-19 neutralizing responses

I Paciello, G Pierleoni, E Pantano, G Antonelli, P Pileri… - Cell Reports, 2024 - cell.com
Understanding the evolution of the B cell response to severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) variants is fundamental to design the next generation of …

Novel omicron variants enhance anchored recognition of TMEM106B: a new pathway for SARS-CoV-2 cellular invasion

X Zhao, F Gao - The Journal of Physical Chemistry Letters, 2024 - ACS Publications
The recent discovery that TMEM106B serves as a receptor mediating ACE2-independent
SARS-CoV-2 entry into cells deserves attention, especially in the background of the frequent …

[HTML][HTML] Humoral and cellular immune responses following Omicron BA. 2.2 breakthrough infection and Omicron BA. 5 reinfection

XJ Zhao, B Ji, C Shang, DY Li, S Zhang, HJ Gu… - Iscience, 2024 - cell.com
The emergence of novel Omicron subvariants has raised concerns regarding the efficacy of
immunity induced by prior Omicron subvariants breakthrough infection (BTI) or reinfection …

[HTML][HTML] Real-time genomic surveillance for enhanced control of infectious diseases and antimicrobial resistance

MJ Struelens, C Ludden, G Werner, V Sintchenko… - Frontiers in …, 2024 - frontiersin.org
This article advocates for mobilizing pathogen genomic surveillance to contain and mitigate
health threats from infectious diseases and antimicrobial resistance (AMR), building upon …

Immune escape of BA. 2.86 is comparable to XBB subvariants from the plasma of BA. 5‐and BA. 5‐XBB‐convalescent subpopulations

X Yang, Y Wang, Z Liang, T Cui, D Chen… - Journal of Medical …, 2024 - Wiley Online Library
Abstract The EG. 5.1 variant of severe acute respiratory syndrome coronavirus‐2 (SARS‐
CoV‐2) has been prevalent since mid‐July 2023 in the United States and China. The variant …

SARS‐CoV‐2 Evolution: Immune Dynamics, Omicron Specificity, and Predictive Modeling in Vaccinated Populations

X Zhang, M Li, N Zhang, Y Li, F Teng, Y Li… - Advanced …, 2024 - Wiley Online Library
Host immunity is central to the virus's spread dynamics, which is significantly influenced by
vaccination and prior infection experiences. In this work, we analyzed the co‐evolution of …