Noise accounts for one-third of hearing loss worldwide. Regretfully, noise-induced hearing
loss (NIHL) is deemed to be irreversible due to the elusive pathogenic mechanisms that …

Cochlear implants can directly activate the auditory system's primary sensory neurons, the
spiral ganglion neurons (SGNs), via circumvention of defective cochlear hair cells. This …

Several studies identified hearing loss as a risk factor for aging-related processes, including
neurodegenerative diseases, as dementia and age-related hearing loss (ARHL). Although …

Noise overexposure leads to hair cell loss, synaptic ribbon reduction, and auditory nerve
deterioration, resulting in transient or permanent hearing loss depending on the exposure …

Significance: The stria vascularis, located in the inner ear, consists of three layers, one of
which is the blood–labyrinth barrier (BLB). It is formed by endothelial cells, sealed together …

Age-related hearing loss (ARHL) is an irreversible, progressive neurodegenerative disorder
and is presently untreatable. Previous studies using animal models have suggested …

Macrophages are the main intrinsic immune cells in the cochlea; they can be activated and
play a complicated role after cochlear injury. Many studies have shown that the number of …

The cochlea encodes sound stimuli and transmits them to the central nervous system, and
damage to sensory cells and synapses in the cochlea leads to hearing loss. The inner ear …

Objective The study aimed to observe the effects of noise exposure on the pericytes of the
cochlear stria vascularis (SV) in mice and to investigate its molecular mechanism. Method …

The auditory system is particularly vulnerable to blast injury due to the ear's role as a highly
sensitive pressure transducer. Over the past several decades, studies have used a variety of …