Dynamic nuclear polarization for sensitivity enhancement in biomolecular solid-state NMR

T Biedenbänder, V Aladin, S Saeidpour… - Chemical …, 2022 - ACS Publications
Solid-state NMR with magic-angle spinning (MAS) is an important method in structural
biology. While NMR can provide invaluable information about local geometry on an atomic …

[HTML][HTML] Dynamic nuclear polarization for sensitivity enhancement in modern solid-state NMR

ASL Thankamony, JJ Wittmann, M Kaushik… - Progress in nuclear …, 2017 - Elsevier
The field of dynamic nuclear polarization has undergone tremendous developments and
diversification since its inception more than 6 decades ago. In this review we provide an in …

Biomolecular and biological applications of solid-state NMR with dynamic nuclear polarization enhancement

WY Chow, G De Paëpe, S Hediger - Chemical Reviews, 2022 - ACS Publications
Solid-state NMR spectroscopy (ssNMR) with magic-angle spinning (MAS) enables the
investigation of biological systems within their native context, such as lipid membranes, viral …

Large molecular weight nitroxide biradicals providing efficient dynamic nuclear polarization at temperatures up to 200 K

A Zagdoun, G Casano, O Ouari… - Journal of the …, 2013 - ACS Publications
A series of seven functionalized nitroxide biradicals (the bTbK biradical and six derivatives)
are investigated as exogenous polarization sources for dynamic nuclear polarization (DNP) …

Oligomeric state and drug binding of the SARS-CoV-2 envelope protein are sensitive to the ectodomain

NH Somberg, I Sučec, J Medeiros-Silva… - Journal of the …, 2024 - ACS Publications
The envelope (E) protein of SARS-CoV-2 is the smallest of the three structural membrane
proteins of the virus. E mediates budding of the progeny virus in the endoplasmic reticulum …

Nuclear depolarization and absolute sensitivity in magic-angle spinning cross effect dynamic nuclear polarization

F Mentink-Vigier, S Paul, D Lee, A Feintuch… - Physical Chemistry …, 2015 - pubs.rsc.org
Over the last two decades solid state Nuclear Magnetic Resonance has witnessed a
breakthrough in increasing the nuclear polarization, and thus experimental sensitivity, with …

Dipolar Recoupling in Rotating Solids

V Ladizhansky, RS Palani, M Mardini… - Chemical …, 2024 - ACS Publications
Magic angle spinning (MAS) nuclear magnetic resonance (NMR) has evolved significantly
over the past three decades and established itself as a vital tool for the structural analysis of …

High-field dynamic nuclear polarization

B Corzilius - Annual review of physical chemistry, 2020 - annualreviews.org
Dynamic nuclear polarization (DNP) is one of the most prominent methods of sensitivity
enhancement in nuclear magnetic resonance (NMR). Even though solid-state DNP under …

The role of cholesterol in M2 clustering and viral budding explained

D Kolokouris, IE Kalenderoglou… - Journal of Chemical …, 2024 - ACS Publications
The influenza A M2 homotetrameric channel consists of four transmembrane (TM) and four
amphipathic helices (AHs). This viral proton channel is suggested to form clusters in the …

Magic Angle Spinning NMR of Proteins: High-Frequency Dynamic Nuclear Polarization and 1H Detection

Y Su, L Andreas, RG Griffin - Annual review of biochemistry, 2015 - annualreviews.org
Magic angle spinning (MAS) NMR studies of amyloid and membrane proteins and large
macromolecular complexes are an important new approach to structural biology. However …