Post-traumatic stress disorder: clinical and translational neuroscience from cells to circuits
Post-traumatic stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder,
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …
characterized by re-experiencing, avoidance, negative emotions and thoughts, and …
Massively parallel techniques for cataloguing the regulome of the human brain
Complex brain disorders are highly heritable and arise from a complex polygenic risk
architecture. Many disease-associated loci are found in non-coding regions that house …
architecture. Many disease-associated loci are found in non-coding regions that house …
Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program
We conducted genome-wide association analyses of over 250,000 participants of European
(EUR) and African (AFR) ancestry from the Million Veteran Program using electronic health …
(EUR) and African (AFR) ancestry from the Million Veteran Program using electronic health …
Sex-based contributors to and consequences of post-traumatic stress disorder
Abstract Purpose of Review Women are twice as likely to develop post-traumatic stress
disorder (PTSD) compared to men after a traumatic experience. The purpose of this mini …
disorder (PTSD) compared to men after a traumatic experience. The purpose of this mini …
[HTML][HTML] Enhancing discovery of genetic variants for posttraumatic stress disorder through integration of quantitative phenotypes and trauma exposure information
Background Posttraumatic stress disorder (PTSD) is heritable and a potential consequence
of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD …
of exposure to traumatic stress. Evidence suggests that a quantitative approach to PTSD …
Integrating human brain proteomes with genome-wide association data implicates novel proteins in post-traumatic stress disorder
Genome-wide association studies (GWAS) have identified several risk loci for post-traumatic
stress disorder (PTSD); however, how they confer PTSD risk remains unclear. We aimed to …
stress disorder (PTSD); however, how they confer PTSD risk remains unclear. We aimed to …
Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, bioinformatic approaches, and recent findings
Major depressive disorder (MDD) is a complex and heterogeneous psychiatric syndrome
with genetic and environmental influences. In addition to neuroanatomical and circuit-level …
with genetic and environmental influences. In addition to neuroanatomical and circuit-level …
Psychopharmacological interaction of alcohol and posttraumatic stress disorder: Effective action of naringin
Posttraumatic stress disorder (PTSD) and alcohol use disorder (AUD) are prevalently co-
occurring, important risk factors for a broad array of neuropsychiatric diseases. To date, how …
occurring, important risk factors for a broad array of neuropsychiatric diseases. To date, how …
Single-nucleus transcriptome profiling of dorsolateral prefrontal cortex: mechanistic roles for neuronal gene expression, including the 17q21. 31 locus, in PTSD stress …
C Chatzinakos, CD Pernia… - American Journal of …, 2023 - Am Psychiatric Assoc
Objective: Multidisciplinary studies of posttraumatic stress disorder (PTSD) and major
depressive disorder (MDD) implicate the dorsolateral prefrontal cortex (DLPFC) in disease …
depressive disorder (MDD) implicate the dorsolateral prefrontal cortex (DLPFC) in disease …
Didymin ameliorates liver fibrosis by alleviating endoplasmic reticulum stress and glycerophospholipid metabolism: based on transcriptomics and metabolomics
Y Li, C Li, Y **ong, B Fang, X Lin… - … design, development and …, 2023 - Taylor & Francis
Introduction Origanum vulgare L. is a traditional Chinese herb, having a strong
hepatoprotective effect. In our previous experiments, we have isolated an ingredient from …
hepatoprotective effect. In our previous experiments, we have isolated an ingredient from …