Glycoproteomics
Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …
proteins and is a crucial protein modification in health and disease. The aim of …
A pragmatic guide to enrichment strategies for mass spectrometry–based glycoproteomics
Glycosylation is a prevalent, yet heterogeneous modification with a broad range of
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
implications in molecular biology. This heterogeneity precludes enrichment strategies that …
Precise, fast and comprehensive analysis of intact glycopeptides and modified glycans with pGlyco3
Great advances have been made in mass spectrometric data interpretation for intact
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …
glycopeptide analysis. However, accurate identification of intact glycopeptides and modified …
Optimal Dissociation Methods Differ for N- and O-Glycopeptides
Site-specific characterization of glycosylation requires intact glycopeptide analysis, and
recent efforts have focused on how to best interrogate glycopeptides using tandem mass …
recent efforts have focused on how to best interrogate glycopeptides using tandem mass …
The human disease gene LYSET is essential for lysosomal enzyme transport and viral infection
Lysosomes are key degradative compartments of the cell. Transport to lysosomes relies on
GlcNAc-1-phosphotransferase–mediated tagging of soluble enzymes with mannose 6 …
GlcNAc-1-phosphotransferase–mediated tagging of soluble enzymes with mannose 6 …
Meta-heterogeneity: evaluating and describing the diversity in glycosylation between sites on the same glycoprotein
Mass spectrometry–based glycoproteomics has gone through some incredible
developments over the last few years. Technological advances in glycopeptide enrichment …
developments over the last few years. Technological advances in glycopeptide enrichment …
[HTML][HTML] Roles of glycosylation at the cancer cell surface: opportunities for large scale glycoproteomics
Cell surface glycosylation has a variety of functions, and its dysregulation in cancer
contributes to impaired signaling, metastasis and the evasion of the immune responses …
contributes to impaired signaling, metastasis and the evasion of the immune responses …
Recent advances in software tools for more generic and precise intact glycopeptide analysis
W Cao, M Liu, S Kong, M Wu, Y Zhang… - Molecular & Cellular …, 2021 - ASBMB
Intact glycopeptide identification has long been known as a key and challenging barrier to
the comprehensive and accurate understanding the role of glycosylation in an organism …
the comprehensive and accurate understanding the role of glycosylation in an organism …
The Hitchhiker's guide to glycoproteomics
Protein glycosylation is one of the most common post-translational modifications that are
essential for cell function across all domains of life. Changes in glycosylation are considered …
essential for cell function across all domains of life. Changes in glycosylation are considered …
Comprehensive analysis of the glycan complement of SARS-CoV-2 spike proteins using signature ions-triggered electron-transfer/higher-energy collisional …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to a global
pandemic of coronavirus disease 2019 (COVID-19). The spike protein expressed on the …
pandemic of coronavirus disease 2019 (COVID-19). The spike protein expressed on the …