The complexities of malaria disease manifestations with a focus on asymptomatic malaria

DD Laishram, PL Sutton, N Nanda, VL Sharma… - Malaria journal, 2012 - Springer
Malaria is a serious parasitic disease in the develo** world, causing high morbidity and
mortality. The pathogenesis of malaria is complex, and the clinical presentation of disease …

Molecular approaches to determine the multiplicity of Plasmodium infections

D Zhong, C Koepfli, L Cui, G Yan - Malaria journal, 2018 - Springer
Multiplicity of infection (MOI), also termed complexity of infection (COI), is defined as the
number of genetically distinct parasite strains co-infecting a single host, which is an …

Plasmodium falciparum msp1 and msp2 genetic diversity and allele frequencies in parasites isolated from symptomatic malaria patients in Bobo-Dioulasso, Burkina …

AF Somé, T Bazié, I Zongo, RS Yerbanga, F Nikiéma… - Parasites & vectors, 2018 - Springer
Abstract Background In Burkina Faso, malaria remains the overall leading cause of
morbidity and mortality accounting for 35.12% of consultations, 40.83% of hospitalizations …

High prevalence of Plasmodium malariae and Plasmodium ovale in co-infections with Plasmodium falciparum in asymptomatic malaria parasite carriers in …

MA Abdulraheem, M Ernest, I Ugwuanyi… - International journal for …, 2022 - Elsevier
Asymptomatic malaria parasite carriers do not seek anti-malarial treatment and may
constitute a silent infectious reservoir. In order to assess the level of asymptomatic and …

Genetically diverse Plasmodium falciparum infections, within-host competition and symptomatic malaria in humans

P Sondo, K Derra, T Lefevre, S Diallo-Nakanabo… - Scientific reports, 2019 - nature.com
There is a large genetic diversity of Plasmodium falciparum strains that infect people
causing diverse malaria symptoms. This study was carried out to explore the effect of mixed …

Understanding P. falciparum Asymptomatic Infections: A Proposition for a Transcriptomic Approach

KM Kimenyi, K Wamae, LI Ochola-Oyier - Frontiers in immunology, 2019 - frontiersin.org
Malaria is still a significant public health burden in the tropics. Infection with malaria causing
parasites results in a wide range of clinical disease presentations, from severe to …

Population genetic structure of Plasmodium falciparum across a region of diverse endemicity in West Africa

VA Mobegi, KM Loua, AD Ahouidi, J Satoguina… - Malaria journal, 2012 - Springer
Background Malaria parasite population genetic structure varies among areas of differing
endemicity, but this has not been systematically studied across Plasmodium falciparum …

Genetic diversity of Plasmodium falciparum infections in mild and severe malaria of children from Kampala, Uganda

MS Kiwuwa, U Ribacke, K Moll, J Byarugaba… - Parasitology …, 2013 - Springer
Diversity in parasite virulence is one of the factors that contribute to the clinical outcome of
malaria infections. The association between the severity of Plasmodium falciparum malaria …

Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination

R Noviyanti, F Coutrier, RAS Utami… - PLoS neglected …, 2015 - journals.plos.org
Background Outside of Africa, P. falciparum and P. vivax usually coexist. In such co-endemic
regions, successful malaria control programs have a greater impact on reducing falciparum …

Multiplicity of Infection and Disease Severity in Plasmodium vivax

MA Pacheco, M Lopez-Perez, AF Vallejo… - PLoS neglected …, 2016 - journals.plos.org
Background Multiplicity of infection (MOI) refers to the average number of distinct parasite
genotypes concurrently infecting a patient. Although several studies have reported on MOI …