Phage therapy: From biological mechanisms to future directions

SA Strathdee, GF Hatfull, VK Mutalik, RT Schooley - Cell, 2023 - cell.com
Increasing antimicrobial resistance rates have revitalized bacteriophage (phage) research,
the natural predators of bacteria discovered over 100 years ago. In order to use phages …

Microbiome and cancer

N Cullin, CA Antunes, R Straussman… - Cancer cell, 2021 - cell.com
The human microbiome constitutes a complex multikingdom community that symbiotically
interacts with the host across multiple body sites. Host-microbiome interactions impact …

Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - journals.asm.org
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

[HTML][HTML] Phage therapy—challenges, opportunities and future prospects

B Zalewska-Piątek - Pharmaceuticals, 2023 - mdpi.com
The increasing drug resistance of bacteria to commonly used antibiotics creates the need to
search for and develop alternative forms of treatment. Phage therapy fits this trend perfectly …

Translating phage therapy into the clinic: Recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - PLoS …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

[HTML][HTML] The safety and toxicity of phage therapy: a review of animal and clinical studies

D Liu, JD Van Belleghem, CR de Vries, E Burgener… - Viruses, 2021 - mdpi.com
Increasing rates of infection by antibiotic resistant bacteria have led to a resurgence of
interest in bacteriophage (phage) therapy. Several phage therapy studies in animals and …

[HTML][HTML] Phage therapy in the resistance era: where do we stand and where are we going?

T Luong, AC Salabarria, DR Roach - Clinical therapeutics, 2020 - Elsevier
Purpose Widespread antibiotic-resistant bacteria are threatening the arsenal of existing
antibiotics. Not only are antibiotics less likely to be effective today, but their extensive use …

Engineered bacteriophage therapeutics: rationale, challenges and future

M Łobocka, K Dąbrowska, A Górski - BioDrugs, 2021 - Springer
The current problems with increasing bacterial resistance to antibacterial therapies, resulting
in a growing frequency of incurable bacterial infections, necessitates the acceleration of …

Alternatives to antibiotics for treatment of mastitis in dairy cows

X Li, C Xu, B Liang, JP Kastelic, B Han… - Frontiers in veterinary …, 2023 - frontiersin.org
Mastitis is considered the costliest disease on dairy farms and also adversely affects animal
welfare. As treatment (and to a lesser extent prevention) of mastitis rely heavily on …