Endometrial cancer (EC) is one of the most common gynecologic cancers and its incidence
is rising globally. Although advanced EC has a poor prognosis; diagnosing EC at an earlier …

Although endometrial cancer management remains challenging, a deeper understanding of
the genetic diversity as well as the drivers of the various pathogenic states of this disease …

Netrin-1 is upregulated in cancers as a protumoural mechanism. Here we describe netrin-1
upregulation in a majority of human endometrial carcinomas (ECs) and demonstrate that …

The functional contribution of myofibroblasts in fibrosis is not well understood,,. Using a new
genetic mouse model to track and isolate myofibroblasts, we performed gene expression …

Simple Summary There are currently no blood biomarkers approved for routine clinical use
in endometrial cancer. Serum human epididymis protein 4 (HE4) is significantly higher in …

Introduction: Endometrial cancer is the most common gynaecological cancer and its
incidence is rising due to increasing obesity rates. We are also seeing an increasing trend of …

Background: The aim of this work was to analyze the diagnostic and prognostic value of
serum human epididymis protein 4 (HE4) and Risk for Ovarian Malignancy Algorithm …

The aim of the study was to explore the clinical value of serum human epididymis secretory
protein E4 (HE4) and CA125 in endometrial carcinoma. From January 2010 to April 2012 …

Objective HE4 has emerged as a promising biomarker in gynaecological oncology. The
purpose of this study was to evaluate serum HE4 as a biomarker for high-risk phenotypes in …

Abstract Human epididymis protein 4 (HE4) has received major attention as a potential
tumor marker in epithelial ovarian cancer; however, evidence of significant overexpression …