The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Tissue tracking technology of routinely acquired cardiovascular magnetic resonance (CMR)
cine acquisitions has increased the apparent ease and availability of non-invasive …

Our understanding of the functions of cardiac fibroblasts has moved beyond their roles in
heart structure and extracellular matrix generation and now includes their contributions to …

The heart is vital for biological function in almost all chordates, including humans. It beats
continually throughout our life, supplying the body with oxygen and nutrients while removing …

Background: Cardiomyocytes are organized in microstructures termed sheetlets that
reorientate during left ventricular thickening. Diffusion tensor cardiac magnetic resonance …

Passive mechanical tissue properties are major determinants of myocardial contraction and
relaxation and, thus, shape cardiac function. Tightly regulated, dynamically adapting …

Mechanical forces will have been omnipresent since the origin of life, and living organisms
have evolved mechanisms to sense, interpret, and respond to mechanical stimuli. The …

Background Cardiac diffusion tensor imaging (cDTI) measures the magnitudes and
directions of intramyocardial water diffusion. Assuming the cross-myocyte components to be …

Purpose Myocardial microstructure has been challenging to probe in vivo. Spin echo–based
diffusion‐weighted sequences allow for single‐shot acquisitions but are highly sensitive to …

Amyloid transthyretin (ATTR) amyloidosis is a protein-misfolding disease characterized by
fibril accumulation in the extracellular space that can result in local tissue disruption and …