Esketamine in depression: putative biomarkers from clinical research

JN Johnston, CA Zarate Jr, MD Kvarta - European Archives of Psychiatry …, 2024 - Springer
The discovery of racemic (R, S)-ketamine as a rapid-acting antidepressant and the
subsequent FDA approval of its (S)-enantiomer, esketamine, for treatment-resistant …

Ketamine and esketamine for depression in daily practice: opportunities and challenges

B Singh - Journal of Clinical Psychopharmacology, 2024 - journals.lww.com
Major depression is a chronic illness where almost 30%–40% of patients do not respond to
conven-tional antidepressants, and for those who do, time to respond is often delayed for …

Metabolic features of adolescent major depressive disorder: A comparative study between treatment-resistant depression and first-episode drug-naive depression

X Gan, X Li, Y Cai, B Yin, Q Pan, T Teng, Y He… - …, 2024 - Elsevier
Major depressive disorder (MDD) is a psychiatric illness that can jeopardize the normal
growth and development of adolescents. Approximately 40% of adolescent patients with …

Facts and myths about use of esketamine for treatment-resistant depression: a narrative clinical review

M Di Vincenzo, V Martiadis, B Della Rocca… - Frontiers in …, 2024 - frontiersin.org
Introduction and aims Treatment-resistant depression (TRD) occurs when at least two
different antidepressants, taken at the right dosage, for adequate period of time and with …

The Polypharmacology of Cariprazine and its Implications to Clinical Indications

A Egyed, DJ Kiss, GM Keserű - … : Strategies for Multi‐Target …, 2025 - Wiley Online Library
This chapter focuses on the third‐generation antipsychotic cariprazine, from its molecular
pharmacology profile to clinical effects. We link the structural features of this bitopic drug with …

An Educational Intervention on the Efficacy of Ketamine Therapy for Treatment-Resistant Depression

VM Wangathika - 2024 - search.proquest.com
Purpose: This quality improvement project aimed to impact participants' knowledge,
knowledge retention, and confidence levels about using ketamine as a treatment method for …

[HTML][HTML] Advances in the Therapeutic Effects of Ketamine on Cancer Pain Related Depression; 11 (3): 653-671

JF Wang, MY Geng, H Yu, Q Yin, W Cheng - transpopmed.org
Pain is a prevalent and significant adverse effect experienced by individuals diagnosed with
cancer. Cancer patients with anxiety and depression can serve to exacerbate their pain …