Optical tweezers have become the method of choice in single-molecule manipulation
studies. In this Primer, we first review the physical principles of optical tweezers and the …

Sarcopenia is a loss of muscle mass and function in the elderly that reduces mobility,
diminishes quality of life, and can lead to fall-related injuries, which require costly …

The widespread use of molecular machines in biology has long suggested that great
rewards could come from bridging the gap between synthetic molecular systems and the …

This review examines intermittent target search strategies, which combine phases of slow
motion, allowing the searcher to detect the target, and phases of fast motion during which …

Detection of single analyte molecules without the use of any label would improve the
sensitivity of current biosensors by orders of magnitude to the ultimate graininess of …

Single actin filaments stabilized with fluorescent phalloidin exhibit ATP-dependent
movement on myosin filaments fixed to a surface. At pH 7.4 and 24 degrees C, the rates of …

Kinesin is a motor protein that uses energy derived from ATP hydrolysis to move organelles
along microtubules. Using a new technique for measuring the movement produced in vitro …

Several enzyme complexes drive cellular movements by coupling free energy-liberating
chemical reactions to the production of mechanical work1–3. A key goal in the study of these …

Multi-color fluorescent nanodiamonds (FNDs) containing a variety of color centers are
promising fluorescent markers for biomedical applications. Compared to colloidal quantum …

Fungal Cell Wall presents a comprehensive examination of the structure, synthesis, and
growth of the fungal cell wall and explores the reasons for the cell wall's importance to the …