The assessment of endothelial function: from research into clinical practice

AJ Flammer, T Anderson, DS Celermajer, MA Creager… - Circulation, 2012 - Am Heart Assoc
The discovery of nitric oxide (NO) as a crucial endothe-lium-derived molecule for vascular
relaxation and the recognition of the endothelium as more than a passive interface between …

Assessment of flow-mediated dilation in humans: a methodological and physiological guideline

DHJ Thijssen, MA Black, KE Pyke… - American Journal …, 2011 - journals.physiology.org
Endothelial dysfunction is now considered an important early event in the development of
atherosclerosis, which precedes gross morphological signs and clinical symptoms. The …

Neurovascular coupling in humans: physiology, methodological advances and clinical implications

AA Phillips, FHN Chan, MMZ Zheng… - Journal of Cerebral …, 2016 - journals.sagepub.com
Neurovascular coupling reflects the close temporal and regional linkage between neural
activity and cerebral blood flow. Although providing mechanistic insight, our understanding …

Republished: Basic science behind the cardiovascular benefits of exercise

MG Wilson, GM Ellison, NT Cable - Postgraduate Medical …, 2015 - academic.oup.com
Cardiorespiratory fitness is a strong predictor of cardiovascular (CV) disease and all-cause
mortality, with increases in cardiorespiratory fitness associated with corresponding …

Troponin and exercise

T Gresslien, S Agewall - International journal of cardiology, 2016 - Elsevier
Cardiac troponins are the preferred biomarkers in diagnostic of myocardial infarction, but
these markers also can rise in response to exercise. Multiple studies have assessed …

Effects of acute exercise on flow-mediated dilatation in healthy humans

EA Dawson, DJ Green… - Journal of applied …, 2013 - journals.physiology.org
Although the effects of exercise training on vascular function have been well studied, less is
known about the effects of acute exercise bouts. This synthesis summarizes and integrates …

Impact of age, sex, and exercise on brachial artery flow-mediated dilatation

MA Black, NT Cable, DHJ Thijssen… - American Journal of …, 2009 - journals.physiology.org
Flow-mediated dilatation (% FMD), an index of nitric oxide (NO)-mediated vasodilator
function, is regarded as a surrogate marker of cardiovascular disease. Aging is associated …

Brief myocardial ischemia produces cardiac troponin I release and focal myocyte apoptosis in the absence of pathological infarction in swine

BR Weil, RF Young, X Shen, G Suzuki, J Qu… - Basic to Translational …, 2017 - jacc.org
In a porcine model of brief ischemia leading to reversible stunning in the absence of tissue
necrosis, we demonstrated delayed release of cardiac troponin I (cTnI) that exceeded the …

Exercise and vascular adaptation in asymptomatic humans

DJ Green, A Spence, JR Halliwill… - Experimental …, 2011 - Wiley Online Library
Beneficial effects of exercise training on the vasculature have been consistently reported in
subjects with cardiovascular risk factors or disease, whereas studies in apparently healthy …

Recommendations in post-exercise hypotension: concerns, best practices and interpretation

LC De Brito, RY Fecchio, T Peçanha… - … journal of sports …, 2019 - thieme-connect.com
Post-exercise hypotension (PEH) is a clinically relevant phenomenon that has been widely
investigated. However, the characteristics of study designs, such as familiarization to blood …