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Precision medicine in stroke: towards personalized outcome predictions using artificial intelligence
Stroke ranks among the leading causes for morbidity and mortality worldwide. New and
continuously improving treatment options such as thrombolysis and thrombectomy have …
continuously improving treatment options such as thrombolysis and thrombectomy have …
Cell death pathways in ischemic stroke and targeted pharmacotherapy
Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
Twenty-year change in severity and outcome of ischemic and hemorrhagic strokes
K Toyoda, S Yoshimura, M Nakai, M Koga… - JAMA …, 2022 - jamanetwork.com
Importance Whether recent changes in demographic characteristics and therapeutic
technologies have altered stroke outcomes remains unknown. Objective To determine …
technologies have altered stroke outcomes remains unknown. Objective To determine …
Age and sex are critical factors in ischemic stroke pathology
Ischemic stroke is a devastating brain injury resulting in high mortality and substantial loss of
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …
function. Understanding the pathophysiology of ischemic stroke risk, mortality, and functional …
Sex differences in presentation of stroke: a systematic review and meta-analysis
Background and Purpose: Women have worse outcomes than men after stroke. Differences
in presentation may lead to misdiagnosis and, in part, explain these disparities. We …
in presentation may lead to misdiagnosis and, in part, explain these disparities. We …
Sex differences in the evaluation and treatment of acute ischaemic stroke
With the greater availability of treatments for acute ischaemic stroke, including advances in
endovascular therapy, personalised assessment of patients before treatment is more …
endovascular therapy, personalised assessment of patients before treatment is more …
Stroke in women—from evidence to inequalities
Stroke is the second largest cause of disability-adjusted life-years lost worldwide. The
prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average …
prevalence of stroke in women is predicted to rise rapidly, owing to the increasing average …
Sex differences in treatment and outcome after stroke: pooled analysis including 19,000 participants
Objective To explore the sex differences in outcomes and management after stroke using a
large sample with high-quality international trial data. Methods Individual participant data …
large sample with high-quality international trial data. Methods Individual participant data …
Reactive astrogliosis in stroke: Contributions of astrocytes to recovery of neurological function
Alterations in neuronal connectivity, particularly in the “peri-infarct” tissue adjacent to the
region of ischemic damage, are important contributors to the spontaneous recovery of …
region of ischemic damage, are important contributors to the spontaneous recovery of …
Sex matters in stroke: a review of recent evidence on the differences between women and men
For the most part, stroke is a disease of old age. With the predicted increase in the aged
population and longer life expectancies, the number and proportion of people living with …
population and longer life expectancies, the number and proportion of people living with …