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Chalcone hybrids as potential anticancer agents: Current development, mechanism of action, and structure‐activity relationship
F Gao, G Huang, J **ao - Medicinal research reviews, 2020 - Wiley Online Library
The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …
agents have been the major challenges in the control and treatment of cancer, making an …
Recent advances in biological active sulfonamide based hybrid compounds Part A: Two-component sulfonamide hybrids
Sulfonamides constitute an important class of drugs, with many types of pharmacological
agents possessing antibacterial, anti-carbonic anhydrase, anti-obesity, diuretic …
agents possessing antibacterial, anti-carbonic anhydrase, anti-obesity, diuretic …
Synthesis of some novel coumarin isoxazol sulfonamide hybrid compounds, 3D-QSAR studies, and antibacterial evaluation
SN Esfahani, MS Damavandi, P Sadeghi, Z Nazifi… - Scientific reports, 2021 - nature.com
With the progressive and ever-increasing antibacterial resistance pathway, the need for
novel antibiotic design becomes critical. Sulfonamides are one of the more effective …
novel antibiotic design becomes critical. Sulfonamides are one of the more effective …
Sulfonamides: Synthesis and the recent applications in Medicinal Chemistry
This review spotlights sulfonamides from different sides, including history, structure-activity
relationship, chemistry, methods of classification and up to date ways for their synthesis …
relationship, chemistry, methods of classification and up to date ways for their synthesis …
Recent progresses in chalcone derivatives as potential anticancer agents
J Yang, J Lv, S Cheng, T **g, T Meng… - Anti-Cancer Agents …, 2023 - benthamdirect.com
Chalcones are members of the flavonoid family and act as intermediates in the biosynthesis
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …
of flavonoids, which are widespread in plants. Meanwhile, chalcones are important …
[PDF][PDF] Chalcones bearing N, O, and S-heterocycles: Recent notes on their biological significances
B Ardiansah - Journal of Applied Pharmaceutical Science, 2019 - japsonline.com
Because of its relatively easy synthesis, chalcone skeleton has been as a point of interest for
organic and medicinal chemists from research groups worldwide. Chalcone scaffold …
organic and medicinal chemists from research groups worldwide. Chalcone scaffold …
[HTML][HTML] New Chalcone Derivatives Containing 2, 4-Dichlorobenzenesulfonamide Moiety with Anticancer and Antioxidant Properties
A Bułakowska, J Sławiński, A Hering, M Gucwa… - International Journal of …, 2023 - mdpi.com
Chalcones and their derivatives, both natural and synthetic, exhibit diverse biological
activities. In this study, we focused on designing and synthesizing (E)-2, 4-dichloro-N-(4 …
activities. In this study, we focused on designing and synthesizing (E)-2, 4-dichloro-N-(4 …
The photocatalytic rate of ZnO supported onto natural zeolite nanoparticles in the photodegradation of an aromatic amine
F Iazdani, A Nezamzadeh-Ejhieh - Environmental Science and Pollution …, 2021 - Springer
Aniline and its derivate are critical environmental pollutants, and thus, the introduction of an
eco-friendly catalyst for removing them is an important research future. The ZnO supported …
eco-friendly catalyst for removing them is an important research future. The ZnO supported …
[HTML][HTML] A sulfonamide chalcone AMPK activator ameliorates hyperglycemia and diabetic nephropathy in db/db mice
S Kaewin, W Poolsri, GG Korkut, J Patrakka… - Biomedicine & …, 2023 - Elsevier
Diabetic nephropathy (DN) is a serious complication of diabetes mellitus (DM), which
currently lacks effective treatments. AMP-activated protein kinase (AMPK) stimulation by …
currently lacks effective treatments. AMP-activated protein kinase (AMPK) stimulation by …
Novel 3-(pyrazol-4-yl)-2-(1H-indole-3-carbonyl)acrylonitrile derivatives induce intrinsic and extrinsic apoptotic death mediated P53 in HCT116 colon carcinoma
A novel series of α-cyano indolylchalcones was prepared, and their chemical structures
were confirmed based on the different spectral data. Among them, compound 7f was …
were confirmed based on the different spectral data. Among them, compound 7f was …