Ion mobility mass spectrometry (IM-MS) for structural biology: insights gained by measuring mass, charge, and collision cross section
E Christofi, P Barran - Chemical Reviews, 2023 - ACS Publications
The investigation of macromolecular biomolecules with ion mobility mass spectrometry (IM-
MS) techniques has provided substantial insights into the field of structural biology over the …
MS) techniques has provided substantial insights into the field of structural biology over the …
Software tools and approaches for compound identification of LC-MS/MS data in metabolomics
The annotation of small molecules remains a major challenge in untargeted mass
spectrometry-based metabolomics. We here critically discuss structured elucidation …
spectrometry-based metabolomics. We here critically discuss structured elucidation …
Ion mobility collision cross-section atlas for known and unknown metabolite annotation in untargeted metabolomics
The metabolome includes not just known but also unknown metabolites; however,
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …
metabolite annotation remains the bottleneck in untargeted metabolomics. Ion mobility …
Ion mobility mass spectrometry in the omics era: Challenges and opportunities for metabolomics and lipidomics
Researchers worldwide are taking advantage of novel, commercially available,
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …
technologies, such as ion mobility mass spectrometry (IM‐MS), for metabolomics and …
Defining the scope of exposome studies and research needs from a multidisciplinary perspective
The concept of the exposome was introduced over 15 years ago to reflect the important role
that the environment exerts on health and disease. While originally viewed as a call-to-arms …
that the environment exerts on health and disease. While originally viewed as a call-to-arms …
Collision cross section compendium to annotate and predict multi-omic compound identities
Ion mobility mass spectrometry (IM-MS) expands the analyte coverage of existing multi-omic
workflows by providing an additional separation dimension as well as a parameter for …
workflows by providing an additional separation dimension as well as a parameter for …
High-end ion mobility mass spectrometry: A current review of analytical capacity in omics applications and structural investigations
Mass spectrometry-based biomolecular analyses have become permanent fixtures of
academic, industrial, and clinical research settings. The rise in utilization of mass …
academic, industrial, and clinical research settings. The rise in utilization of mass …
The critical role that spectral libraries play in capturing the metabolomics community knowledge
Background Spectral library searching is currently the most common approach for
compound annotation in untargeted metabolomics. Spectral libraries applicable to liquid …
compound annotation in untargeted metabolomics. Spectral libraries applicable to liquid …
Toward healthcare diagnoses by machine-learning-enabled volatile organic compound identification
As a natural monitor of health conditions for human beings, volatile organic compounds
(VOCs) act as significant biomarkers for healthcare monitoring and early stage diagnosis of …
(VOCs) act as significant biomarkers for healthcare monitoring and early stage diagnosis of …
Advanced analytical and informatic strategies for metabolite annotation in untargeted metabolomics
Liquid chromatography–mass spectrometry (LC–MS)-based untargeted metabolomics is
constantly challenged by large-scale and unambiguous metabolite annotation in complex …
constantly challenged by large-scale and unambiguous metabolite annotation in complex …