Restorative effects of ethanolic leaf extract of Datura stramonium against methotrexate-induced hematological impairments
One of the prominent complications observed in those undergoing treatment with
methotrexate (MTX) is hematological profile alterations which could culminate in severe …
methotrexate (MTX) is hematological profile alterations which could culminate in severe …
Spirulina ameliorates methotrexate hepatotoxicity via antioxidant, immune stimulation, and proinflammatory cytokines and apoptotic proteins modulation
Aims Methotrexate (MTX) is an efficient cytotoxic drug used against various carcinogenic,
inflammatory and autoimmune diseases; however, the hepatotoxicity of MTX limits its use …
inflammatory and autoimmune diseases; however, the hepatotoxicity of MTX limits its use …
Apigenin alleviates methotrexate-induced liver and kidney injury in mice
F Sahindokuyucu-Kocasari, Y Akyol… - Human & …, 2021 - journals.sagepub.com
Methotrexate (MTX) is a drug used in the treatment of various types of cancer and
inflammatory diseases, but its clinical use has been restricted due to its toxicity. Apigenin …
inflammatory diseases, but its clinical use has been restricted due to its toxicity. Apigenin …
L-methionine protects against nephrotoxicity induced by methotrexate through modulation of redox status and inflammation
Objective: Methotrexate (MTX) is a drug used in the treatment of cancer and autoimmune
disorders; however, its clinical use is limited because of serious side effects including renal …
disorders; however, its clinical use is limited because of serious side effects including renal …
Cardamonin (2′, 4′-dihydroxy-6′-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats
Abstract Boesenbergia rotunda (L.) Mansf. had been traditionally used as herbs to treat pain
and rheumatism. Cardamonin (2′, 4′-dihydroxy-6′-methoxychalcone) is a compound …
and rheumatism. Cardamonin (2′, 4′-dihydroxy-6′-methoxychalcone) is a compound …
[PDF][PDF] Methotrexate induced hepatotoxicity and its management
S Kumari, S Kumari, AK Sharma, I Kaur - Inter J Sci Res, 2016 - academia.edu
Liver dysfunction is a major health problem that challenges not only health care
professionals but also the pharmaceutical industry and drug regulatory agencies. Commonly …
professionals but also the pharmaceutical industry and drug regulatory agencies. Commonly …
[PDF][PDF] The investigation of the oxidative stress-related parameters in high doses methotrexate-induced albino Wistar rats
S Saka, O Aouacheri - J Bioequiv Availab, 2017 - researchgate.net
Methotrexate (MTX) is used as a chemotherapeutic agent used to treat many cancer types.
Methotrexate was known for its toxic effects involving most of the body organs including liver …
Methotrexate was known for its toxic effects involving most of the body organs including liver …
In vivo anti-psoriatic activity, biodistribution, sub-acute and sub-chronic toxicity studies of orally administered methotrexate loaded chitin nanogel in comparison with …
The anti-psoriatic efficacy of orally administered methotrexate loaded chitin nanogel
(MCNG) was evaluated (two doses-2.715 mg/kg and 5.143 mg/kg) and compared against …
(MCNG) was evaluated (two doses-2.715 mg/kg and 5.143 mg/kg) and compared against …
Protective effect of dexpanthenol against methotrexate-induced liver oxidative toxicity in rats
Methotrexate is a familiar chemotherapeutic preferred in a wide range of clinical fields such
as leukemia, psoriasis, rheumatoid arthritis, neoplastic and autoimmune disorders …
as leukemia, psoriasis, rheumatoid arthritis, neoplastic and autoimmune disorders …
Protective effect of Morinda citrifolia L. (fruit extract) on methotrexate-induced toxicities—hematological and biochemical studies
Methotrexate (MTX) has been widely used as an anticancer drug. It acts as a folic acid
analog, inhibits purine and pyrimidine synthesis, which accounts for its efficacy in the …
analog, inhibits purine and pyrimidine synthesis, which accounts for its efficacy in the …