Oxidative stress is a component of many diseases, including atherosclerosis, chronic
obstructive pulmonary disease, Alzheimer disease and cancer. Although numerous small …

Idiopathic pulmonary fibrosis (IPF) is a progressive, lethal fibrotic lung disease that occurs
primarily in middle-aged and elderly adults. It is a major cause of morbidity and mortality …

Most chronic inflammatory illnesses include fibrosis as a pathogenic characteristic.
Extracellular matrix (ECM) components build up in excess to cause fibrosis or scarring. The …

Cardiovascular disease (CVD) is a major cause of mortality worldwide. A better
understanding of the mechanisms underlying CVD is key for better management or …

(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

Interstitial lung diseases (ILDs) comprise different fibrotic lung disorders characterized by
cellular proliferation, interstitial inflammation, and fibrosis. The JAK/STAT molecular pathway …

Idiopathic pulmonary fibrosis (IPF) is a chronic progressive disease characterized by
excessive proliferation of fibroblasts and excessive accumulation of extracellular matrix …

Background Cigarette smoking (CS) is a strong risk factor for idiopathic pulmonary fibrosis
(IPF). It can activate lung fibroblasts (LF) by inducing redox imbalance. We previously …

Pulmonary fibrosis (PF) is a progressive, and life-threatening interstitial lung disease which
causes scarring in the lung parenchyma and thereby affects architecture and functioning of …

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal interstitial lung disease. During
the past decade, novel pathogenic mechanisms of IPF have been elucidated that have …