The global emergence of zoonotic viruses, including poxviruses, poses one of the greatest
threats to human and animal health. Forty years after the eradication of smallpox, emerging …

Abstract Safety tested Modified Vaccinia virus Ankara (MVA) is licensed as third-generation
vaccine against smallpox and serves as a potent vector system for development of new …

Monkeypox virus (MPXV) was discovered in 1958 during an outbreak in an animal facility in
Copenhagen, Denmark. Since its discovery, MPXV has revealed a propensity to infect and …

Zoonotic orthopoxvirus outbreaks have occurred repeatedly worldwide, including
monkeypox in Africa and the United States, cowpox in Europe, camelpox in the Middle East …

In the age of COVID, nucleic acid vaccines have garnered much attention, at least in part,
because of the simplicity of construction, production, and flexibility to adjust and adapt to an …

The Poxviridae family is comprised of double-stranded DNA viruses belonging to
nucleocytoplasmic large DNA viruses (NCLDV). Among the NCLDV, poxviruses exhibit the …

This review provides a brief history of the impacts that a human-specific Orthopoxvirus
(OPXV), Variola virus, had on mankind, recalls how critical vaccination was for the …

The increasing frequency of monkeypox virus infections, new outbreaks of other zoonotic
orthopoxviruses and concern about the re-emergence of smallpox have prompted research …

The monkeypox virus (MPXV) outbreak, primarily endemic to Africa, has spread globally,
with Brazil reporting the second-highest number of cases. The emergence of MPXV in non …

The orthopoxviruses (OPV) comprise several emerging viruses with great importance to
human and veterinary medicine, including vaccinia virus (VACV), which causes outbreaks of …