Multiple ion isolation and accumulation events for selective chemical noise reduction and dynamic range enhancement in MALDI imaging mass spectrometry

TR Scoggins, JT Specker, BM Prentice - Analyst, 2024 - pubs.rsc.org
Abundant chemical noise in MALDI imaging mass spectrometry experiments can impede the
detection of less abundant compounds of interest. This chemical noise commonly originates …

Imaging with mass spectrometry: Which ionization technique is best?

BM Prentice - Journal of Mass Spectrometry, 2024 - Wiley Online Library
The use of mass spectrometry (MS) to acquire molecular images of biological tissues and
other substrates has developed into an indispensable analytical tool over the past 25 years …

Formation of multiple ion types during MALDI imaging mass spectrometry analysis of Mitragyna speciosa alkaloids in dosed rat brain tissue

Z Liang, Y Guo, N Ellin, TI King, EC Berthold… - Talanta, 2024 - Elsevier
Mitragyna speciosa, more commonly known as kratom, has emerged as an alternative to
treat chronic pain and addiction. However, the alkaloid components of kratom, which are the …

[HTML][HTML] A multi-modal image fusion workflow incorporating MALDI imaging mass spectrometry and microscopy for the study of small pharmaceutical compounds

Z Liang, Y Guo, A Sharma, CR McCurdy, BM Prentice - bioRxiv, 2024 - ncbi.nlm.nih.gov
Multi-modal imaging analyses of dosed tissue samples can provide more comprehensive
insight into the effects of a therapeutically active compound on a target tissue compared to …