Multiphoton microscopy (MPM) has found a niche in the world of biological imaging as the
best noninvasive means of fluorescence microscopy in tissue explants and living animals …

Although the nonlinear optical effect known as second-harmonic generation (SHG) has
been recognized since the earliest days of laser physics and was demonstrated through a …

Second-harmonic generation (SHG) microscopy has emerged as a powerful modality for
imaging fibrillar collagen in a diverse range of tissues. Because of its underlying physical …

The ability to obtain a molecular-level understanding of the chemistry that takes place at
liquid/solid interfaces is key to the development and improvement of many chemical and …

Coherent anti-Stokes Raman scattering (CARS) microscopy permits vibrational imaging with
high-sensitivity, high speed, and three-dimensional spatial resolution. We review recent …

We find that several key endogenous protein structures give rise to intense second-
harmonic generation (SHG)—nonabsorptive frequency doubling of an excitation laser line …

In the last decades, imaging membrane potential has become a fruitful approach to study
neural circuits, especially in invertebrate preparations with large, resilient neurons. At the …

Multiphoton microscopy relies on nonlinear light–matter interactions to provide contrast and
optical sectioning capability for high-resolution imaging. Most multiphoton microscopy …

A key concept underlying the specific functionalities of metasurfaces is the use of constituent
components to shape the wavefront of the light on demand. Metasurfaces are versatile …

Collagen is the most important structural protein of the animal body. Its unique triple-helix
structure and extremely high level of crystallinity make it exceptionally efficient in generating …