The assay for transposase-accessible chromatin using sequencing (ATAC-seq) provides a
simple and scalable way to detect the unique chromatin landscape associated with a cell …

Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …

Persistent DNA double-strand breaks (DSBs) in neurons are an early pathological hallmark
of neurodegenerative diseases including Alzheimer's disease (AD), with the potential to …

Chemical synapses between axons and dendrites mediate neuronal intercellular
communication. Here, we describe a synapse between axons and primary cilia: the axo …

The characteristics of the sleep drivers and the mechanisms through which sleep relieves
the cellular homeostatic pressure are unclear. In flies, zebrafish, mice, and humans, DNA …

Memory, defined as the storage and use of learned information in the brain, is necessary to
modulate behavior and critical for animals to adapt to their environments and survive …

Early-life stress (ELS) is one of the strongest lifetime risk factors for depression, anxiety,
suicide, and other psychiatric disorders, particularly after facing additional stressful events …

Erasing traumatic memory during memory reconsolidation is a promising retrieval-extinction
strategy for post-traumatic stress disorder (PTSD). Here, we developed an acute social …

The activity of neurons in the rodent hippocampus contributes to diverse behaviors, with the
activity of ventral hippocampal neurons affecting behaviors related to anxiety and emotion …

Stroke causes death of brain tissue leading to long-term deficits. Behavioral evidence from
neurorehabilitative therapies suggest learning-induced neuroplasticity can lead to beneficial …