High levels of mitochondrial dynamics, autophagy, and apoptosis contribute to stable testicular status in hibernating Daurian ground squirrels

Z Wang, MD Wang, XC Wang, L Chen, LF Li… - … and Physiology Part A …, 2024‏ - Elsevier
Daurian ground squirrels (Spermophilus dauricus) experience various stress states during
winter hibernation, but the impact on testicular function remains unclear. This study focused …

Seasonal expressions of the translocator protein (18 kDa), voltage-dependent anion channel, and steroidogenic acute regulatory protein in the scent glands of …

W **e, Q Gao, P Chen, H Zhang, Y Liu… - The Journal of Steroid …, 2023‏ - Elsevier
Steroidogenesis machinery involves the steroidogenic acute regulatory protein (StAR),
which regulates cholesterol transfer within the mitochondria, and the transport of cholesterol …

Seasonal change of circulating leptin associated with testicular activities of the wild ground squirrels (Citellus dauricus)

W Yu, S Fan, X Wang, J Zhu, Z Yuan, Y Han… - Integrative …, 2023‏ - Wiley Online Library
The purpose of this study was to explore the variations in the circulating leptin
concentrations of the wild ground squirrels in relation to seasonal changes in testicular …

[HTML][HTML] Seasonal Changes in the Distinct Taxonomy and Function of the Gut Microbiota in the Wild Ground Squirrel (Spermophilus dauricus)

X Yang, Y Yao, X Zhang, J Zhong, F Gao, H Zhang… - Animals, 2021‏ - mdpi.com
Simple Summary Gut microbiota is a large number of microbes colonized in the gut tract,
and it plays a certain role in regulating the host's immunity, metabolism, and nervous system …

Ponicidin Promotes Hepatocellular Carcinoma Mitochondrial Apoptosis by Stabilizing Keap1‐PGAM5 Complex

B Zhao, Z Liang, L Zhang, L Jiang, Y Xu… - Advanced …, 2024‏ - Wiley Online Library
Ponicidin is a diterpenoid with demonstrated antitumor activity in clinical trials. However, the
specific function and mechanism of action against hepatocellular carcinoma (HCC) remain …

Metabolic adaptation mechanisms of glycogen reduction and lipid accumulation in testicular protection in Daurian ground squirrels during hibernation

MD Wang, LF Li, YJ Yan, XC Wang, L Chen, K Dang… - Biochimie, 2025‏ - Elsevier
The role of glycogen and lipid metabolism in the testes of Daurian ground squirrels
(Spermophilus dauricus) during different stages of the hibernation cycle and their influence …

Seasonal changes of mitochondrial autophagy and oxidative response in the testis of the wild ground squirrels (Spermophilus dauricus)

Y Wang, R Su, P Liu, Z Yuan, Y Han… - American Journal …, 2021‏ - journals.physiology.org
Mitochondria are the main organelles for mammalian energy metabolism and have been
implicated in the regulation of germ cell maintenance and spermatogenesis. However, little …

Seasonal expressions of oxytocin and oxytocin receptor in the epididymides in the wild ground squirrels (Citellus dauricus Brandt)

Z Yuan, Y Wang, W Yu, W **e, Z Zhang, J Wang… - General and …, 2020‏ - Elsevier
The aim of this study was to detect the seasonal expressions of oxytocin (OT), oxytocin
receptor (OTR), extracellular signal-regulated kinase1 and 2 (ERK1/2) and phospho-ERK1/2 …

Spermatocytes are the terminals of germ cell differentiation in plateau zokor (Eospalax baileyi) during the non‐breeding season

K An, B Yao, Y Tan, Y Kang, Z Wang, J Su - Integrative Zoology, 2024‏ - Wiley Online Library
Plateau zokor (Eospalax baileyi) is a subterranean rodent and seasonal breeder. During the
non‐breeding season, the testicles regress, leading to the arrest of spermatogenesis and …

Seasonal Expression of Gonadotropin Genes in the Pituitary and Testes of Male Plateau Zokor (Eospalax baileyi)

K An, B Yao, Y Kang, M Bao, Y Tan, Q Pu, J Su - Animals, 2022‏ - mdpi.com
Simple Summary The plateau zokor lives on the Qinghai-Tibet Plateau and is a local
endemic subterranean rodent. As a result of climate change and human activities, the …