Natural rubber biosynthesis in plants, the rubber transferase complex, and metabolic engineering progress and prospects

S Cherian, SB Ryu, K Cornish - Plant biotechnology journal, 2019 - Wiley Online Library
Natural rubber (NR) is a nonfungible and valuable biopolymer, used to manufacture~ 50
000 rubber products, including tires and medical gloves. Current production of NR is derived …

Plant molecular engine out of the chassis: Natural rubber synthesis in cell-free systems

AW Umar, JC Park, T Ling, SB Ryu - Industrial Crops and Products, 2023 - Elsevier
Natural rubber (NR) is one of the most important polymers and is used in more than 40,000
products. The demand for NR is estimated to reach $68.5 billion in 2026. The key …

Orthogonal Engineering of Biosynthetic Pathway for Efficient Production of Limonene in Saccharomyces cerevisiae

S Cheng, X Liu, G Jiang, J Wu, J Zhang… - ACS Synthetic …, 2019 - ACS Publications
Limonene, a plant-derived natural cyclic monoterpene, is widely used in the pharmaceutical,
food, and cosmetics industries. The conventional limonene biosynthetic (CLB) pathway in …

Biochemical composition of Hevea brasiliensis latex: A focus on the protein, lipid, carbohydrate and mineral contents

C Bottier - Advances in Botanical Research, 2020 - Elsevier
The latex collected from the Hevea brasiliensis tree is today the only commercial source of
natural rubber (NR), the cis-1, 4-polyisoprene polymer, a strategic raw material. The Hevea …

New insights into natural rubber biosynthesis from rubber‐deficient lettuce mutants expressing goldenrod or guayule cis‐prenyltransferase

M Kwon, CL Hodgins, EM Salama, KR Dias… - New …, 2023 - Wiley Online Library
Lettuce produces natural rubber (NR) with an average M w of> 1 million Da in laticifers,
similar to NR from rubber trees. As lettuce is an annual, self‐pollinating, and easily …

Another level of complex-ity: The role of metabolic channeling and metabolons in plant terpenoid metabolism

M Gutensohn, E Hartzell, N Dudareva - Frontiers in Plant Science, 2022 - frontiersin.org
Terpenoids constitute one of the largest and most diverse classes of plant metabolites. While
some terpenoids are involved in essential plant processes such as photosynthesis …

Structural elucidation of the cis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation

BH Edani, KA Grabińska, R Zhang… - Proceedings of the …, 2020 - National Acad Sciences
Cis-prenyltransferase (cis-PTase) catalyzes the rate-limiting step in the synthesis of glycosyl
carrier lipids required for protein glycosylation in the lumen of endoplasmic reticulum. Here …

RNASeq analysis of drought-stressed guayule reveals the role of gene transcription for modulating rubber, resin, and carbohydrate synthesis

C Dong, G Ponciano, N Huo, Y Gu, D Ilut… - Scientific Reports, 2021 - nature.com
The drought-adapted shrub guayule (Parthenium argentatum) produces rubber, a natural
product of major commercial importance, and two co-products with potential industrial use …

Overexpressing an Arabidopsis SEIPIN1 reduces rubber particle size in guayule

GQ Chen, G Ponciano, C Dong, N Dong… - Industrial Crops and …, 2023 - Elsevier
A conventional source of natural rubber (NR) is from Hevea (Hevea brasiliensis). NR
production from Hevea is limited by its narrow growth region and susceptibility to leaf blight …

Molecular genetic analysis of natural rubber biosynthesis

AY Amerik, YT Martirosyan, LY Martirosyan… - Russian Journal of Plant …, 2021 - Springer
Abstract Natural rubber (cis-1, 4-polyisoprene) is an irreplaceable starting material for
thousands of products, many of which are absolutely essential, in particular for modern …