Skeletal muscle methylome and transcriptome integration reveals profound sex differences related to muscle function and substrate metabolism
Nearly all human complex traits and diseases exhibit some degree of sex differences, with
epigenetics being one of the main contributing factors. Various tissues display sex …
epigenetics being one of the main contributing factors. Various tissues display sex …
LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness
I Pallavicini, TM Frasconi, C Catozzi, E Ceccacci… - Nature …, 2024 - nature.com
The lysine-specific histone demethylase 1 A (LSD1) is involved in antitumor immunity;
however, its role in sha** CD8+ T cell (CTL) differentiation and function remains largely …
however, its role in sha** CD8+ T cell (CTL) differentiation and function remains largely …
[HTML][HTML] Blood RNA biomarkers for tuberculosis screening in people living with HIV before antiretroviral therapy initiation: a diagnostic accuracy study
T Mann, RK Gupta, BWP Reeve… - The Lancet Global …, 2024 - thelancet.com
Background Undiagnosed tuberculosis remains a major threat for people living with HIV.
Multiple blood transcriptomic biomarkers have shown promise for tuberculosis diagnosis …
Multiple blood transcriptomic biomarkers have shown promise for tuberculosis diagnosis …