Immune-based therapies such as immune checkpoint inhibitors have revolutionized the
systemic treatment of various cancer types. The therapeutic application of monoclonal …

Abstract Mucosal Associated Invariant T (MAIT) cells are evolutionary conserved innate-like
T cells able to recognize bacterial and fungal ligands derived from vitamin B biosynthesis …

Peritoneal metastasis is the leading cause of death for gastrointestinal cancers. The native
and therapy-induced ascites ecosystems are not fully understood. Here, we characterize …

Receptor-interacting protein kinase 3 (RIPK3), a member of the receptor-interacting protein
kinase (RIPK) family with serine/threonine protein kinase activity, interacts with RIPK1 to …

Spondyloarthritis (SpA) refers to a group of diseases with inflammation in joints and spines.
In this family, ankylosing spondylitis (AS) is a rare but classic form that mainly involves the …

Tumour microenvironment (TME) is crucial to tumorigenesis. This study aimed to uncover
the differences in immune phenotypes of TME in endometrial cancer (EC) using Uterine …

Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells that
recognize non-peptide antigens including riboflavin derivates. Although in vitro–activated …

Mucosal-associated invariant T (MAIT) cells play diverse roles in cancer, infectious
diseases, and immunotherapy. This review explores their intricate involvement in cancer …

Mucosa-associated invariant T (MAIT) cells are the largest population of unconventional T
cells in humans. These antimicrobial T cells are poised with rapid effector responses …

Mucosal-associated Invariant T (MAIT) cells recognize vitamin B-based antigens presented
by the non-polymorphic MHC class I related-1 molecule (MR1). Both MAIT T cell receptors …