Exploiting nanomaterials for optical coherence tomography and photoacoustic imaging in nanodentistry

A Das, GCC Raposo, DS Lopes, EJ da Silva… - Nanomaterials, 2022 - mdpi.com
There is already a societal awareness of the growing impact of nanoscience and
nanotechnology, with nanomaterials (with at least one dimension less than 100 nm) now …

Functional imaging for regenerative medicine

M Leahy, K Thompson, H Zafar, S Alexandrov… - Stem Cell Research & …, 2016 - Springer
In vivo imaging is a platform technology with the power to put function in its natural structural
context. With the drive to translate stem cell therapies into pre-clinical and clinical trials, early …

In vivo detection of nanometer-scale structural changes of the human tympanic membrane in otitis media

R Dsouza, J Won, GL Monroy, MC Hill, RG Porter… - Scientific reports, 2018 - nature.com
Otitis media (OM) is a common ear infection and a leading cause of conductive hearing loss
in the pediatric population. Current technologies such as otoscopy, pneumatic otoscopy …

Nanosensitive optical coherence tomography to assess wound healing within the cornea

C Lal, S Alexandrov, S Rani, Y Zhou, T Ritter… - Biomedical Optics …, 2020 - opg.optica.org
Optical coherence tomography (OCT) is a non-invasive depth resolved optical imaging
modality, that enables high resolution, cross-sectional imaging in biological tissues and …

Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal

S Alexandrov, A Arangath, Y Zhou, M Murphy… - Scientific Reports, 2021 - nature.com
Optical coherence tomography (OCT) is a rapidly evolving technology with a broad range of
applications, including biomedical imaging and diagnosis. Conventional intensity-based …

Depth enhancement in spectral domain optical coherence tomography using bidirectional imaging modality with a single spectrometer

NK Ravichandran, RE Wijesinghe… - … of biomedical optics, 2016 - spiedigitallibrary.org
A method for depth enhancement is presented using a bidirectional imaging modality for
spectral domain optical coherence tomography (SD-OCT). Two precisely aligned sample …

Dynamic single gold nanoparticle visualization by clinical intracoronary optical coherence tomography

J Hu, F Rivero, RA Torres, H Loro Ramirez… - Journal of …, 2017 - Wiley Online Library
The potential use of Gold Nanoparticles (GNPs) as contrast agents for clinical intracoronary
frequency domain Optical Coherence Tomography (OCT) is here explored. The OCT …

Skin cancer margin detection using nanosensitive optical coherence tomography and a comparative study with confocal microscopy

R Dey, S Alexandrov, P Owens, J Kelly… - Biomedical Optics …, 2022 - opg.optica.org
Excision biopsy and histology represent the gold standard for morphological investigation of
the skin, in particular for cancer diagnostics. Nevertheless, a biopsy may alter the original …

Characterization of nanosensitive multifractality in submicron scale tissue morphology and its alteration in tumor progression

N Das, S Alexandrov, KE Gilligan… - … of biomedical optics, 2021 - spiedigitallibrary.org
Significance: Assessment of disease using optical coherence tomography is an actively
investigated problem, owing to many unresolved challenges in early disease detection …

Nanosensitive optical coherence tomography for detecting structural changes in stem cells

A Arangath, N Duffy, S Alexandrov, S James… - Biomedical Optics …, 2023 - opg.optica.org
Mesenchymal stromal cells (MSCs) are adult stem cells that have been widely investigated
for their potential to regenerate damaged and diseased tissues. Multiple pre-clinical studies …