Risk factors for early-onset colorectal cancer: a systematic review and meta-analysis

DE O'Sullivan, RL Sutherland, S Town, K Chow… - Clinical …, 2022 - Elsevier
Background & Aims Despite the widespread increase in the incidence of early-onset
colorectal cancer (EoCRC), the reasons for this increase remain unclear. The objective of …

Cancer therapy–related hypertension: a scientific statement from the American Heart Association

JB Cohen, NJ Brown, SA Brown, S Dent… - …, 2023 - Am Heart Assoc
Contemporary anticancer drugs have significantly improved cancer survival at the expense
of cardiovascular toxicities, including heart disease, thromboembolic disease, and …

Ferroptosis: a double-edged sword mediating immune tolerance of cancer

Q Dang, Z Sun, Y Wang, L Wang, Z Liu, X Han - Cell death & disease, 2022 - nature.com
The term ferroptosis was put forward in 2012 and has been researched exponentially over
the past few years. Ferroptosis is an unconventional pattern of iron-dependent programmed …

Metabolic dysfunction and obesity‐related cancer: beyond obesity and metabolic syndrome

P Karra, M Winn, S Pauleck, A Bulsiewicz‐Jacobsen… - …, 2022 - Wiley Online Library
Objectives: The metabolic dysfunction driven by obesity, including hyperglycemia and
dyslipidemia, increases risk for develo** at least 13 cancer types. The concept of …

Epidemiology of renal cell carcinoma: 2022 update

L Bukavina, K Bensalah, F Bray, M Carlo… - European urology, 2022 - Elsevier
Context International variations in the rates of kidney cancer (KC) are considerable. An
understanding of the risk factors for KC development is necessary to generate opportunities …

Hypertension and prohypertensive antineoplastic therapies in cancer patients

DCH Van Dorst, SJH Dobbin, KB Neves… - Circulation …, 2021 - Am Heart Assoc
The development of a wide range of novel antineoplastic therapies has improved the
prognosis for patients with a wide range of malignancies, which has increased the number …

Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients

T Siggaard, R Reguant, IF Jørgensen, AD Haue… - Nature …, 2020 - nature.com
Abstract We present the Danish Disease Trajectory Browser (DTB), a tool for exploring
almost 25 years of data from the Danish National Patient Register. In the dataset comprising …

Antihypertensive treatment and risk of cancer: an individual participant data meta-analysis

E Copland, D Canoy, M Nazarzadeh, Z Bidel… - The Lancet …, 2021 - thelancet.com
Background Some studies have suggested a link between antihypertensive medication and
cancer, but the evidence is so far inconclusive. Thus, we aimed to investigate this …

Reverse cardio‐oncology: cancer development in patients with cardiovascular disease

JP Aboumsallem, J Moslehi… - Journal of the American …, 2020 - Am Heart Assoc
Overwhelming epidemiological evidence demonstrate that cardiovascular disease and
cancer represent major health burdens in the United States, and they are the leading causes …

Development and internal-external validation of statistical and machine learning models for breast cancer prognostication: cohort study

AK Clift, D Dodwell, S Lord, S Petrou, M Brady… - bmj, 2023 - bmj.com
Objective To develop a clinically useful model that estimates the 10 year risk of breast
cancer related mortality in women (self-reported female sex) with breast cancer of any stage …