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Fluorescence‐Based HTS Assays for Ion Channel Modulation in Drug Discovery Pipelines
J Voldřich, M Matoušová, M Šmídková… - …, 2024 - Wiley Online Library
Ion channels represent a druggable family of transmembrane pore‐forming proteins with
important (patho) physiological functions. While electrophysiological measurement (manual …
important (patho) physiological functions. While electrophysiological measurement (manual …
[HTML][HTML] Elucidation of medusozoan (jellyfish) venom constituent activities using constellation pharmacology
AA Yanagihara, ML Giglio, K Hurwitz, R Kadler… - Toxins, 2024 - mdpi.com
Within the phylum Cnidaria, sea anemones (class Anthozoa) express a rich diversity of ion-
channel peptide modulators with biomedical applications, but corollary discoveries from …
channel peptide modulators with biomedical applications, but corollary discoveries from …
NeuriteNet: A convolutional neural network for assessing morphological parameters of neurite growth
Background During development or regeneration, neurons extend processes (ie., neurites)
via mechanisms that can be readily analyzed in culture. However, defining the impact of a …
via mechanisms that can be readily analyzed in culture. However, defining the impact of a …
Deep Learning and Explainable AI in Medical Image Segmentation
S Mullan - 2023 - search.proquest.com
Medical imaging is a critical part of modern healthcare, and the continued advancement of
imaging techniques have enabled the analysis of an every growing number of objects and …
imaging techniques have enabled the analysis of an every growing number of objects and …
[PDF][PDF] Deep learning and explainable AI in medical imaging
S Mullan - 2023 - iro.uiowa.edu
Medical imaging is a critical part of modern healthcare, and the continued advancement of
imaging techniques have enabled the analysis of an every growing number of objects and …
imaging techniques have enabled the analysis of an every growing number of objects and …
Characterization of Calcium binding protein 1 (CaBP1/Caldendrin) expression and function in dorsal root ganglion neurons
JA Lopez - 2021 - search.proquest.com
The dorsal root ganglion (DRG) is a cluster of heterogenous neurons that are responsible for
transmitting sensory input signals such as touch, pain, and temperature from the periphery to …
transmitting sensory input signals such as touch, pain, and temperature from the periphery to …
NeuriteNet: A Convolutional Neural Network for determining morphological differences in neurite growth
Background During development or regeneration, neurons extend processes (ie, neurites)
via mechanisms that can be readily analyzed in culture. However, defining the impact of a …
via mechanisms that can be readily analyzed in culture. However, defining the impact of a …