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Neuroinflammation in Alzheimer disease
Increasing evidence points to a pivotal role of immune processes in the pathogenesis of
Alzheimer disease, which is the most prevalent neurodegenerative and dementia-causing …
Alzheimer disease, which is the most prevalent neurodegenerative and dementia-causing …
[HTML][HTML] Long COVID: pathophysiological factors and abnormalities of coagulation
S Turner, MA Khan, D Putrino, A Woodcock… - Trends in Endocrinology …, 2023 - cell.com
Acute COVID-19 infection is followed by prolonged symptoms in approximately one in ten
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …
cases: known as Long COVID. The disease affects~ 65 million individuals worldwide. Many …
Transforming the understanding of brain immunity
Contemporary studies have completely changed the view of brain immunity from envisioning
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …
the brain as isolated and inaccessible to peripheral immune cells to an organ in close …
Revisiting the neurovascular unit
S Schaeffer, C Iadecola - Nature neuroscience, 2021 - nature.com
The brain is supplied by an elaborate vascular network that originates extracranially and
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
reaches deep into the brain. The concept of the neurovascular unit provides a useful …
Insights into Alzheimer's disease from single-cell genomic approaches
Alzheimer's disease (AD) is an age-related disease pathologically defined by the deposition
of amyloid plaques and neurofibrillary tangles in the brain parenchyma. Single-cell profiling …
of amyloid plaques and neurofibrillary tangles in the brain parenchyma. Single-cell profiling …
Peripheral and central immune system crosstalk in Alzheimer disease—a research prospectus
BM Bettcher, MG Tansey, G Dorothée… - Nature Reviews …, 2021 - nature.com
Dysregulation of the immune system is a cardinal feature of Alzheimer disease (AD), and a
considerable body of evidence indicates pathological alterations in central and peripheral …
considerable body of evidence indicates pathological alterations in central and peripheral …
SARS CoV‐2 related microvascular damage and symptoms during and after COVID‐19: Consequences of capillary transit‐time changes, tissue hypoxia and …
L Østergaard - Physiological reports, 2021 - Wiley Online Library
Abstract Corona virus disease 2019 (COVID‐19) causes symptoms from multiple organs
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …
after infection by severe acute respiratory syndrome corona virus 2 (SARS CoV‐2). They …
Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology
Aging accounts for increased risk and dismal outcome of ischemic stroke. Here, we
investigated the impact of age-related changes in the immune system on stroke. Upon …
investigated the impact of age-related changes in the immune system on stroke. Upon …
[HTML][HTML] Alzheimer disease: an update on pathobiology and treatment strategies
Alzheimer disease (AD) is a heterogeneous disease with a complex pathobiology. The
presence of extracellular β-amyloid deposition as neuritic plaques and intracellular …
presence of extracellular β-amyloid deposition as neuritic plaques and intracellular …
The neurovasculome: key roles in brain health and cognitive impairment: a scientific statement from the American Heart Association/American Stroke Association
Background: Preservation of brain health has emerged as a leading public health priority for
the aging world population. Advances in neurovascular biology have revealed an intricate …
the aging world population. Advances in neurovascular biology have revealed an intricate …